7 10

Cited 0 times in

A Comprehensive Analysis of Clinical Trials in the COVID-19 Pandemic Era

Authors
 Jinhee Lee  ;  Han Wul Shin  ;  Jun Young Lee  ;  Jae Seok Kim  ;  Jae Won Yang  ;  Keum Hwa Lee  ;  Andreas Kronbichler  ;  Jae Il Shin 
Citation
 MEDICINA-LITHUANIA, Vol.56(6) : 315, 2020-06 
Journal Title
 MEDICINA-LITHUANIA 
ISSN
 1010-660X 
Issue Date
2020-06
MeSH
Clinical Trials as Topic / statistics & numerical data* ; Coronavirus Infections / therapy* ; Databases, Factual ; Humans ; Pandemics ; Pneumonia, Viral / therapy*
Keywords
COVID-19 ; clinical trials
Abstract
Background and objective: Despite medical advances, we are facing the unprecedented disaster of the coronavirus disease 2019 (COVID-19) pandemic without available treatments and effective vaccines. As the COVID-19 pandemic has approached its culmination, desperate efforts have been made to seek proper treatments and response strategies, and the number of clinical trials has been rapidly increasing. In this time of the pandemic, it is believed that learning lessons from it would be meaningful in preparing for future pandemics. Thus, this study aims at providing a comprehensive landscape of COVID-19 related clinical trials based on the ClinicalTrials.gov database. Materials and methods: Up to 30 March 2020, we identified a total of 147 eligible clinical trials and reviewed the overview of the studies. Results: Until then, the most clinical trials were set up in China. Treatment approaches are the most frequent purpose of the registered studies. Chloroquine, interferon, and antiviral agents such as remdesivir, lopinavir, and ritonavir are agents under investigation in these trials. Conclusions: In this study, we introduced the promising therapeutic options that many researchers and clinicians are interested in, and to address the hidden issues behind clinical trials in this COVID-19 pandemic.
Files in This Item:
T202002548.pdf Download
DOI
10.3390/medicina56060315
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아청소년과학교실) > 1. Journal Papers
Yonsei Authors
Shin, Jae Il(신재일) ORCID logo https://orcid.org/0000-0003-2326-1820
Lee, Keum Hwa(이금화) ORCID logo https://orcid.org/0000-0002-1511-9587
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/179370
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse

Links