Cited 8 times in
Pro-inflammatory Cytokine Levels and Cancer-related Fatigue in Breast Cancer Survivors: Effects of an Exercise Adherence Program
DC Field | Value | Language |
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dc.contributor.author | 이향규 | - |
dc.contributor.author | 김수 | - |
dc.contributor.author | 한지희 | - |
dc.date.accessioned | 2020-09-28T02:48:24Z | - |
dc.date.available | 2020-09-28T02:48:24Z | - |
dc.date.issued | 2020-04 | - |
dc.identifier.issn | 1738-6756 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/179131 | - |
dc.description.abstract | Purpose: This study aimed to determine the effect of an exercise intervention on subjective cancer-related fatigue (CRF) and pro-inflammatory cytokine levels in breast cancer survivors (BCS). Methods: BCS with greater than moderate CRF (≥ 4) were recruited and randomly assigned to experimental or control groups. The experimental group participated in a 12-week exercise adherence program (Better Life after Cancer - Energy, Strength, and Support; BLESS). Interleukin (IL)-6 and tumor necrosis factor-α (TNF-α) levels were determined at 3 time points (M1: baseline, M2: post-intervention, and M4: 6 months after intervention). Subjective fatigue was measured using the Korean version of the revised Piper Fatigue Scale. Results: In this analysis of participants with physiological fatigue measures available (19 experimental, 21 control), there were no statistically significant differences in IL-6 (F = 1.157, p = 0.341), TNF-α levels (F = 0.878, p = 0.436), and level of fatigue (F = 2.067, p = 0.118) between the 2 groups at baseline. Fatigue in the experimental group showed statistically significant improvement compared to the control only at M2 (p = 0.022). There was no significant relationship between subjective and physiological fatigue at the 3 measurement points. Conclusion: The BLESS intervention improved CRF in BCS immediately at post-intervention, and this study presents clinical feasibility for the management of CRF in BCS in the early survivorship phase who are already experiencing fatigue. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | Korean, English | - |
dc.publisher | Korean Breast Cancer Society | - |
dc.relation.isPartOf | JOURNAL OF BREAST CANCER | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Pro-inflammatory Cytokine Levels and Cancer-related Fatigue in Breast Cancer Survivors: Effects of an Exercise Adherence Program | - |
dc.type | Article | - |
dc.contributor.college | College of Nursing (간호대학) | - |
dc.contributor.department | Dept. of Nursing (간호학과) | - |
dc.contributor.googleauthor | Sung Hae Kim | - |
dc.contributor.googleauthor | Yoon Kyung Song | - |
dc.contributor.googleauthor | Jeehee Han | - |
dc.contributor.googleauthor | Yun Hee Ko | - |
dc.contributor.googleauthor | Hyojin Lee | - |
dc.contributor.googleauthor | Min Jae Kang | - |
dc.contributor.googleauthor | Hyunki Park | - |
dc.contributor.googleauthor | Hyangkyu Lee | - |
dc.contributor.googleauthor | Sue Kim | - |
dc.identifier.doi | 10.4048/jbc.2020.23.e22 | - |
dc.contributor.localId | A03282 | - |
dc.contributor.localId | A00629 | - |
dc.relation.journalcode | J01279 | - |
dc.identifier.eissn | 2092-9900 | - |
dc.identifier.pmid | 32395379 | - |
dc.subject.keyword | Breast neoplasms | - |
dc.subject.keyword | Cytokines | - |
dc.subject.keyword | Exercise | - |
dc.subject.keyword | Fatigue | - |
dc.contributor.alternativeName | Lee, Hyang Kyu | - |
dc.contributor.affiliatedAuthor | 이향규 | - |
dc.contributor.affiliatedAuthor | 김수 | - |
dc.citation.volume | 23 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 205 | - |
dc.citation.endPage | 217 | - |
dc.identifier.bibliographicCitation | JOURNAL OF BREAST CANCER, Vol.23(2) : 205-217, 2020-04 | - |
dc.identifier.rimsid | 67498 | - |
dc.type.rims | ART | - |
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