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Validation of the Korean Version of the Questionnaire for Impulsive-Compulsive Disorders in Parkinson's Disease Rating Scale

 Ji Hyun Choi  ;  Jee Young Lee  ;  Jin Whan Cho  ;  Seong Beom Ko  ;  Tae Beom Ahn  ;  Sang Jin Kim  ;  Sang Myung Cheon  ;  Joong Seok Kim  ;  Yoon Joong Kim  ;  Hyeo Il Ma  ;  Jong Sam Baik  ;  Phil Hyu Lee  ;  Sun Ju Chung  ;  Jong Min Kim  ;  In Uk Song  ;  Han Joon Kim  ;  Young Hee Sung  ;  Do Young Kwon  ;  Jae Hyeok Lee  ;  Ji Young Kim  ;  Ji Sun Kim  ;  Ji Young Yun  ;  Hee Jin Kim  ;  Jin Yong Hong  ;  Mi Jung Kim  ;  Jinyoung Youn  ;  Ji Seon Kim  ;  Eung Seok Oh  ;  Hui Jun Yang  ;  Won Tae Yoon  ;  Sooyeoun You  ;  Kyum Yil Kwon  ;  Hyung Eun Park  ;  Su Yun Lee  ;  Younsoo Kim  ;  Hee Tae Kim  ;  Mee Young Park 
 JOURNAL OF CLINICAL NEUROLOGY, Vol.16(2) : 245-253, 2020-04 
Journal Title
Issue Date
compulsive behavior ; impulsive behavior ; parkinson disease ; rating scale ; validation study
Background and purpose: Impulse-control disorder is an important nonmotor symptom of Parkinson's disease (PD) that can lead to financial and social problems, and be related to a poor quality of life. A nationwide multicenter prospective study was performed with the aim of validating the Korean Version of the Questionnaire for Impulsive-Compulsive Disorders in Parkinson's Disease Rating Scale (K-QUIP-RS).

Methods: The K-QUIP-RS was constructed using forward and backward translation, and pretesting of the prefinal version. PD patients on stable medical condition were recruited from 27 movement-disorder clinics. Participants were assessed using the K-QUIP-RS and evaluated for parkinsonian motor and nonmotor statuses and for PD-related quality of life using a predefined evaluation battery. The test-retest reliability of the K-QUIP-RS was assessed over an interval of 10-14 days, and correlations between the KQUIP-RS and other clinical scales were analyzed.

Results: This study enrolled 136 patients. The internal consistency of the K-QUIP-RS was indicated by a Cronbach's α coefficient of 0.846, as was the test-retest reliability by a Guttman split-half coefficient of 0.808. The total K-QUIP-RS score was positively correlated with the scores for depression and motivation items on the Unified PD Rating Scale (UPDRS), Montgomery-Asberg Depression Scale, and Rapid-Eye-Movement Sleep-Behavior-Disorders Questionnaire. The total K-QUIP-RS score was also correlated with the scores on part II of the UPDRS and the PD Quality of Life-39 questionnaire, and the dopaminergic medication dose.

Conclusions: The K-QUIP-RS appears to be a reliable assessment tool for impulse-control and related behavioral disturbances in the Korean PD population.
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1. College of Medicine (의과대학) > Dept. of Neurology (신경과학교실) > 1. Journal Papers
Yonsei Authors
Lee, Phil Hyu(이필휴) ORCID logo https://orcid.org/0000-0001-9931-8462
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