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A retrospective study of the clinical outcomes and significant variables in the surgical treatment of temporal lobe tumor associated with intractable seizures

Authors
 Jae Young Choi  ;  Jin Woo Chang  ;  Yong Gou Park  ;  Tai Seung Kim  ;  Byung In Lee  ;  Sang Sup Chung 
Citation
 STEREOTACTIC AND FUNCTIONAL NEUROSURGERY, Vol.82(1) : 35-42, 2004-03 
Journal Title
 STEREOTACTIC AND FUNCTIONAL NEUROSURGERY 
ISSN
 1011-6125 
Issue Date
2004-03
MeSH
Adolescent ; Adult ; Brain Neoplasms / complications ; Brain Neoplasms / pathology ; Brain Neoplasms / surgery* ; Female ; Humans ; Magnetic Resonance Imaging / methods ; Male ; Middle Aged ; Retrospective Studies ; Seizures / complications ; Seizures / pathology ; Seizures / surgery* ; Statistics, Nonparametric ; Temporal Lobe / pathology ; Temporal Lobe / surgery* ; Treatment Outcome
Abstract
A retrospective study was performed assessing the preoperative evaluation, and the postoperative outcomes in 35 patients with a temporal lobe tumor with intractable seizures who were treated by our neurosurgery service between October 1995 and December 1999. The mean age of the patients at the time of surgery was 27.9 years. The period of follow-up after surgery was a mean of 33.0 months. Of the study group of 35 patients, 27 (77.1%) became completely seizure free after surgery (class I), and 2 patients (5.7%) had no more than 2 seizures per year (class II). Worthwhile seizure control was achieved in 29 patients (82.8%). There was a statistical significance between the extent of tumor resection and favorable seizure outcome (p = 0.014). The most frequent histopathological diagnoses were classic epilepsy-associated ganglioglioma in 16 (45.7%) patients and low-grade astrocytoma in 10 (28.6%) patients. Complete resection of tumor was the most significant factor in obtaining a favorable seizure outcome.
Full Text
https://www.karger.com/Article/Abstract/76659
DOI
10.1159/000076659
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurosurgery (신경외과학교실) > 1. Journal Papers
Yonsei Authors
Chang, Jin Woo(장진우) ORCID logo https://orcid.org/0000-0002-2717-0101
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/178867
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