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Pyodermatitis-pyostomatitis vegetans with circulating autoantibodies to bullous pemphigoid antigen 230

Authors
 Bong Kyun Ahn  ;  Soo-Chan Kim 
Citation
 JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, Vol.50(5) : 785-788, 2004-05 
Journal Title
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
ISSN
 0190-9622 
Issue Date
2004-05
MeSH
Adult ; Autoantibodies / blood* ; Autoantigens / immunology* ; Basement Membrane / immunology ; Carrier Proteins ; Collagen / immunology* ; Cytoskeletal Proteins ; Dystonin ; Female ; Gingivitis, Necrotizing Ulcerative / complications ; Gingivitis, Necrotizing Ulcerative / immunology* ; Gingivitis, Necrotizing Ulcerative / pathology ; Humans ; Immunoblotting ; Immunoglobulin G / blood ; Microscopy, Immunoelectron ; Nerve Tissue Proteins ; Non-Fibrillar Collagens* ; Pyoderma / immunology* ; Pyoderma / pathology ; Skin Diseases, Vesiculobullous / complications ; Skin Diseases, Vesiculobullous / immunology* ; Skin Diseases, Vesiculobullous / pathology
Abstract
We describe a woman from Korea with pyodermatitis-pyostomatitis vegetans associated with ulcerative colitis. On immunofluorescence examination, she demonstrated in vivo bound and circulating IgG antibasement membrane zone antibodies. The immunoelectron microscopy and immunoblot analysis showed that the antibodies reacted with the bullous pemphigoid antigen 230. We consider that the circulating autoantibodies to the bullous pemphigoid antigen 230 in this patient were an epiphenomenon, resulting from epidermal damage induced by inflammation of pyodermatitis-pyostomatitis vegetans.
Full Text
https://www.sciencedirect.com/science/article/pii/S0190962203033036
DOI
10.1016/j.jaad.2003.09.007
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Dermatology (피부과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Soo Chan(김수찬) ORCID logo https://orcid.org/0000-0002-2327-4755
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/178818
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