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Relationship between environmental tobacco smoke and urinary cotinine levels in passive smokers at their residence

Authors
 Hyojin Kim 1 , Youngwook Lim, Seokju Lee, Soungeun Park, Changsoo Kim, Cheinsoo Hong, Dongchun Shin 
Citation
 JOURNAL OF EXPOSURE ANALYSIS AND ENVIRONMENTAL EPIDEMIOLOGY, Vol.14(1) : S65-S70, 2004-01 
Journal Title
 JOURNAL OF EXPOSURE ANALYSIS AND ENVIRONMENTAL EPIDEMIOLOGY 
ISSN
 1053-4245 
Issue Date
2004-01
MeSH
Adult ; Aged ; Air Pollution, Indoor / analysis* ; Biomarkers / analysis* ; Chromatography, High Pressure Liquid ; Cotinine / urine* ; Environmental Exposure* ; Female ; Gas Chromatography-Mass Spectrometry ; Housing ; Humans ; Male ; Middle Aged ; Sensitivity and Specificity ; Tobacco Smoke Pollution / analysis*
Abstract
Studies of the health effects of environmental tobacco smoke (ETS) using measured air concentrations are subject to bias. Cotinine, a nicotine metabolite detected in urine, has been recommended as a quantitative measure of nicotine intake and thus as a marker for ETS exposure in humans. The aim of this study was to correlate home indoor ETS levels with passive smokers' urinary cotinine levels. The urinary cotinine concentrations of 57 non-smoking women who spend >19 h a day at home and the nicotine levels in their living room air were measured over a period of 24 h. Nicotine and urinary cotinine levels were analyzed using GC/MS and HPLC/UV, respectively. In addition, information was collected regarding the smoking habits of the subjects' families. A significant correlation was found between the nicotine levels in indoor air and the urinary cotinine to creatinine ratio of the passive smokers. The smoking habits of the subjects' family members were also correlated to the urinary cotinine levels of the passive smokers.
Full Text
https://www.nature.com/articles/7500360
DOI
10.1038/sj.jea.7500360
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Hong, Chein Soo(홍천수)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/178814
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