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Monotherapy in Patients with Type 2 Diabetes Mellitus

Authors
 Sang Youl Rhee  ;  Hyun Jin Kim  ;  Seung-Hyun Ko  ;  Kyu-Yeon Hur  ;  Nan-Hee Kim  ;  Min Kyong Moon  ;  Seok-O Park  ;  Byung-Wan Lee  ;  Kyung Mook Choi  ;  Jin Hwa Kim 
Citation
 DIABETES & METABOLISM JOURNAL, Vol.41(5) : 349-356, 2017-10 
Journal Title
 DIABETES & METABOLISM JOURNAL 
ISSN
 2233-6079 
Issue Date
2017-10
Keywords
Diabetes mellitus, type 2 ; Hypoglycemic agents ; Metformin ; Practice guideline
Abstract
In order to improve the quality of life and to prevent chronic complications related to diabetes mellitus, intensive lifestyle modification and proper medication are needed from the early stage of diagnosis of type 2 diabetes mellitus (T2DM). When using the first medication for diabetic patients, the appropriate treatment should be selected considering the clinical characteristics of the patient, efficacy of the drug, side effects, and cost. In general, the use of metformin as the first treatment for oral hypoglycemic monotherapy is recommended because of its excellent blood glucose-lowering effect, relatively low side effects, long-term proven safety, low risk of hypoglycemia, and low weight gain. If metformin is difficult to use as a first-line treatment, other appropriate medications should be selected in view of the clinical situation. If the goal of achieving glycemic control is not achieved by monotherapy, a combination therapy with different mechanisms of action should be initiated promptly.
Files in This Item:
T201706479.pdf Download
DOI
10.4093/dmj.2017.41.5.349
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Lee, Byung Wan(이병완) ORCID logo https://orcid.org/0000-0002-9899-4992
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/178322
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