In the paper, studies in genetis, reward system, role of neurotransmitters, especially dopamine and opiate system, other
biological causes and drug treatments were reviewed. Based
on biological hypothesis, various forms of drug treatment have
been developed. Treatment for detoxification, for prevention
and treatment of withdrawal symptoms, for alcholism-related
mental disorders, for craving and for avoiding drinking behavior
were reviewed, too. As biological mechanisms in alcoholism
will be clarified in the future, it is expected that new treatment method with specific drugs will be available.