144 103

Cited 0 times in

알레르기 피부반응시험상 아스페르길루스 항원에 양성 반응을 보인 천식 환자에서 알레르기성 기관지-폐 아스페르길루스증의 유병률

Authors
 박중원  ;  김희선  ;  변주원  ;  고시환  ;  홍용국  ;  김철우  ;  최규옥  ;  홍천수 
Citation
 Journal of Asthma, Allergy and Clinical Immunology (천식 및 알레르기), Vol.17(4) : 510-521, 1997 
Journal Title
Journal of Asthma, Allergy and Clinical Immunology(천식 및 알레르기)
ISSN
 1226-8739 
Issue Date
1997
Abstract
Objective .' The incidence of ABPA was quite different according to the countries and the prevalence of ABPA has not been reported in Korea. In this study, we evaluated the prevalence of ABPA in asthmatics with positive skin reactivity to Aspergillus fumigatus (Af). Methods '. Ninety asthmatics with positive skin reactivity to Af were enrolled. The ABPA were diagnosed by the Greenburg and Pettersons criteria or by the pathologic features of lung. Results . Six cases out of 90 asthmatics (6.7 were diagnosed as ABPA (ABPA group). Total IgE level were not significantly different between ABPA group and asthmatics with Af skin reactivity (BA group n= 84) Five out of 6 ABPA had higher than 1000 ng/ml of total IgE and all six cases had more than 600/ul of peripheral blood eosinophil counts. Only two cases had the positive immunoprecipitin band to Af antigen. Antibody index of Af specific IgE and IgG in ABPA group were 5.58+3.35, 2.75+1.29, respectively and coutruls were. Three cases of ABPA had central bronchiectasis, two case has only infiltrative lung lesions, one case with destructive lung lesions and another one cases have no pulmonary pathologic lesion at chest radiology but with the serologic evidence of ABPA. Although we could not find statistical significance, the FEV, (70.1+ 27.0% vs 87.8+23.2%) and PEFR (71.8+30.6% vs 95. 0+ 26.5% ) of ABPA group were lower than those of BA group. Conclusion .'These results suggest that ABPA is not uncommon in Af sensitized asthmatics in Korea. We thought that initial examination of allergic skin test including Aspergillus should be emphasized for screening the ABPA in Korean asthmatics.
Files in This Item:
T199702954.pdf Download
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Park, Jung Won(박중원) ORCID logo https://orcid.org/0000-0003-0249-8749
Hong, Chein Soo(홍천수)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/178027
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse

Links