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유방암환자의 효소면역법과 면역조직화학법에 의한 호르몬수용체, 조직학적 분화도 및 유방촬영술소견과의 상관관계

Other Titles
 Relation Between Hormone Receptor (Enzyme-Immunoassay and Immunohistochemistry), Histologic Grade and Mammographic Findings in Patients with Primary Breast Cancer 
 강병철  ;  오기근  ;  김재근  ;  정우희  ;  이희대  ;  송경순 
 Journal of the Korean Cancer Association (대한암학회지), Vol.29(1) : 53-61, 1997 
Journal Title
 Journal of the Korean Cancer Association (대한암학회지) 
Issue Date
Breast cancer ; Mammography ; Hormone receptor (estrogen receptor)
PURPOSE: To evaluate the relationship between the hormone receptor status, histologic grade and, the film-mammographic findings in primary breast cancer. MATERIALS AND METHODS: 198 breast cancer patients with hormonal receptor assay were included in this study. Estrogen receptor (ER) and progesterone receptor (PR) were determined by immunohistochemical method and enzyme-immunoassay. And film-mammographic findings were evaluated to disclose the relationship among the three variables (film-mmamographic findings, histologic grade and hormonal receptor status). Film- mammographic findings of the breast cancer are classified as spiculation, increased parenchymal density, calcification and mass. RESULTS: There is no correlation between estrogen receptor and histologic grade in 154 patients. Some correlation between estrogen receptor by enzyme-immunoassay and by immunohistochemistrical methods with 28 available data were observed (R=0.428). Among high estrogen receptor (ER) patients, there is a high possibility of spiculation or mass in mammography with 79 available data (Modified t-test, P<0.01). CONCLUSION: Spiculation or/and mass of the mammography can be related to the high possibile factor of the positive estrogen receptor or high level of estrogen receptor in primary breast cancer.
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1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
Yonsei Authors
Jung, Woo Hee(정우희)
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