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개심술시 Autologous Platelet-Rich Plasma가 술후 출혈량과 수혈요구량에 미치는 영향

Other Titles
 Effects of Autologous Platelet-Rich Plasma on Postoperative Blood Loss and Transfusion Requirements in Cardiac Surgery 
 홍용우  ;  유은숙  ;  방서욱  ;  곽영란  ;  송근호  ;  이춘수  ;  남상벌  ;  김명옥 
 Journal of Korean Society of Anesthesiologist (대한마취과학회지), Vol.32(6) : 953-958, 1997 
Journal Title
 Journal of Korean Society of Anesthesiologist (대한마취과학회지) 
Issue Date
Transfusion ; platelet-rich plasmapheresis ; Surgery ; cardiac
BACKGROUND Patients undergoing cardiac surgery employing cardiopulmonary bypass frequently require transfusion of homologous blood products and, therefore, are exposed to the risk of transfusions. A administration of autologous platelet-rich plasma may reduce homologous transfusion and attendant risks. This study was designed to investigate the effect of preoperative collection of platelet-rich plasma on the requirement of homologous transfusion and postoperative blood loss in patients undergoing open heart surgery. METHODS Twenty seven patients undergoing cardiac surgery were divided into control group(n=11) and autologous platelet-rich plasmaphereris(PRP) group(n=16). Autologous platelet-rich plasma was retransfused after offbypass. Hematocrit, platelet count, PT(prothrombin time), PTT(partial thromboplastin time), postoperative blood loss and transfusion requirement were measured. RESULTS There was no statistical significance between control and PRP group in homologous transfusion and postoperative blood loss. There was no difference in hemoatocrit, platelet count, PT or PTT on immediate post surgery or on day 1. CONCLUSIONS Autologous platelet-rich plasma did not reduce postoperative blood loss or transfusion reguirements in cardiac surgery.
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1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers
Yonsei Authors
Kwak, Young Lan(곽영란) ORCID logo https://orcid.org/0000-0002-2984-9927
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