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전이성 악성 림프종에 의한 중추성 요붕증 1예

Other Titles
 A Case of Central Diabetes Insipidus Caused by Metastatin Malignant Lymphoma 
 이상학  ;  송영득  ;  김현수  ;  이유미  ;  윤용석  ;  남재현  ;  권석호  ;  김경래  ;  임승길  ;  이현철  ;  허갈범 
 Endocrinology and Metabolism (대한내분비학회지), Vol.12(4) : 596-601, 1997 
Journal Title
 Endocrinology and Metabolism (대한내분비학회지) 
Issue Date
The causes of central diabetes insipidus(CDI) are numerous; some primary cases are idiopathic while most secondary cases are surgically induced or the result of tumor. The frequency of metastatic tumor as a cause of DI is 6% to 20% of cases, Variety of malignancies including breast, lung, colon, prostate cancer, and leukemia/lymphoma have been reported to metastasize to the pituitary, although most patients are asymptomatic. Clinical manifestations of pituitary metastases include anterior pituitary failure, visual disturbance, and extraocular muscle weakness. DI is the most common clinical manifestation of hypothalamic-pituitary axis(HPA) metastases. Anatomical basis far this clinical picture is that most metastases occur in the posterior lobe. We report on a 35-year-old male patient with meningeal involvement of malignant lymphoma that was thought to be associated with DI. Confirmation of primary malignancy was made by biopsy at site of cervical lymph node and tonsil, Pituitary involvement was suspected on brain MRI, and satisfactory symptornatic relief was obtained with vasopressin. Because of the progres- sion of underlying lymphorna that has shown no response to combined anticancer chemotherapy, the patient expired on 60th hospital day. (J Korean Soc Endocrinol 12:596-601, 1997)
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Lee, Hyun Chul(이현철)
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