배양된 치주인대세포와 티타늄과의 접촉면의 구조

Abstract

A particular problem associated with osseointegrated implants is the fact that the implants lack a periodontal ligament. Thereby, marginal inflammation around an implant may cause more serious bone loss than does marginal inflammation around teeth with a periodontal ligament. In addition, osseointegrated implants are ankylosed and do not haute the same mobility as natural teeth with a periodontal ligament. Implants with a periodontal ligament would eliminate these problems. In order to explore the possibility of producing a periodontal ligament around titanium dental implants, a study of the attachment of cultured periodontal ligament cells to titanium was carried out. Periodontal ligament cells obtained from premolar teeth of individuals undergoing tooth extraction for orthodontic reasons were cultured on titanium-coated epon blocks. Sections of the blocks were cut perpendicular to the surface of the cell layer. Transmission electron microscopy of the periodntal ligament cells/titanium interface showed that there was no evidence of attachment at the cultured periodontal ligament cells titanium interface. The microfilaments, commonly located adjacent to the titanium surface, run mostly parallel to the titanium surface. The study showed that cultured periodontal ligament cells did not create an attachment structure on a titanium surface similar to that of natural teeth.