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Coronary Stenting (Cordis) Without Anticoagulation

Authors
 Seong-Wook Park  ;  Seung-Jung Park  ;  Myeong-Ki Hong  ;  Jae-Joong Kim  ;  Seung-Yun Cho  ;  Yang-Soo Jang  ;  Kwon-Bae Kim  ;  Kee-Sik Kim  ;  Dong-Joo Oh  ;  Byung-Hee Oh  ;  Jung-Chaee Kang 
Citation
 AMERICAN JOURNAL OF CARDIOLOGY, Vol.79(7) : 901-904, 1997 
Journal Title
 AMERICAN JOURNAL OF CARDIOLOGY 
ISSN
 0002-9149 
Issue Date
1997
MeSH
Anticoagulants/therapeutic use* ; Aspirin/therapeutic use ; Coronary Angiography ; Coronary Disease/therapy* ; Coronary Thrombosis/diagnostic imaging ; Coronary Thrombosis/prevention & control* ; Evaluation Studies as Topic ; Fibrinolytic Agents/therapeutic use* ; Humans ; Middle Aged ; Platelet Aggregation Inhibitors/therapeutic use ; Stents* ; Ticlopidine/therapeutic use ; Time Factors ; Warfarin/therapeutic use
Abstract
We evaluated the effect of antithrombotic regimens on subacute thrombosis and short-term clinical courses after successful implantation of the Cordis coronary stent, which is a flexible, balloon expandable, radiopaque tantalum stent. Two hundred seventy-five consecutive patients with 290 lesions were treated with 356 Cordis stent implantations. According to poststent antithrombotic regimen, patients were divided into 3 groups; 165 patients with 175 lesions received aspirin 200 mg/day, ticlopidine 500 mg/day, and warfarin for 1 month (group 1), 66 patients with 69 lesions received aspirin and ticlopidine (group 2), and 44 patients with 46 lesions received aspirin alone (group 3) after successful Cordis stenting. The overall procedural success rates were 97.7% in group 1, 98.6% in group 2, and 100% in group 3. More than 65% of the patients were eligible for elective stenting. The overall rate of stent thrombosis was 1.8%: 1.2% in patients assigned to the treatment with aspirin, ticlopidine, and warfarin; 0% in patients with aspirin and ticlopidine; and 6.8% in patients assigned to the treatment with aspirin alone. In conclusion, the Cordis coronary stent is an effective endovascular stent in various clinical indications including unstable angina and acute myocardial infarction. Antiplatelet therapy using aspirin and ticlopidine after successful Cordis coronary stenting is a promising alternative to anticoagulation therapy to overcome the drawbacks of stenting. However, poststent antithrombotic therapy with aspirin alone is associated with a significant rate of stent thrombosis.
Full Text
https://www.sciencedirect.com/science/article/pii/S0002914997000179?via%3Dihub
DOI
10.1016/s0002-9149(97)00017-9
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Jang, Yang Soo(장양수) ORCID logo https://orcid.org/0000-0002-2169-3112
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/177412
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