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Do hematocrit and serum fibrinogen influence transcranial Doppler measurements?

Authors
 Young Ho Sohn  ;  Gyung Whan Kim  ;  Jin-Soo Kim 
Citation
 JOURNAL OF KOREAN MEDICAL SCIENCE, Vol.12(5) : 405-408, 1997 
Journal Title
 JOURNAL OF KOREAN MEDICAL SCIENCE 
ISSN
 1011-8934 
Issue Date
1997
MeSH
Adult ; Aged ; Female ; Fibrinogen/physiology* ; Hematocrit* ; Humans ; Male ; Middle Aged ; Prospective Studies ; Ultrasonography, Doppler, Transcranial*
Abstract
To investigate the effect of hematocrit and serum fibrinogen on transcranial Doppler ultrasound (TCD) measurements, we performed, TCD tests and measured hematocrit and serum fibrinogen concentrations in 112 healthy adult volunteers. The mean velocities of the middle cerebral (r = -.37, p < .0001), internal carotid at siphon (r = -.14, p < .05) and cervical level (r = -.14, p < .05), vertebral (r = -.21, p < .005) and the basilar artery (r = -.33, p < .001) were significantly and inversely correlated with hematocrit, while serum fibrinogen weakly affected the mean velocities of the internal carotid artery. The subjects with low hematocrit (< or = 40%) showed significantly higher mean velocities of the middle cerebral, vertebral and basilar arteries than those with high hematocrit (> 40%). Considering the influence of the subject's age and gender, hematocrit is the strongest factor influencing the velocities of the middle cerebral and the basilar artery. These results suggest that hematocrit is an important variable for TCD measurements of the cerebral blood velocities and should be taken into account in TCD application.
Files in This Item:
T199700923.pdf Download
DOI
10.3346/jkms.1997.12.5.405
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurology (신경과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Gyung Whan(김경환) ORCID logo https://orcid.org/0000-0001-7053-4372
Sohn, Young Ho(손영호) ORCID logo https://orcid.org/0000-0001-6533-2610
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/177332
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