성견의 1면 골내낭에서 탈회냉동건조골과 Calcium sulfate혼합이식이 치주조직 치유에 미치는 영향

Abstract

The present study evaluates the effects of calcium sulfate and DFDB on alveolar bone regeneration and cementum formation and connective tissue adhesion in intrabony angulated 1 wall defects of dogs. Four millimeter-deep angulated one-wall intrabony defects were surgically created in the mesial & distal aspects of premolars and with flap operaion alone(control group), with calcium sulfate(experimental group 1), with composit graft of 50% calcium sulfate and 50% DFDB(experimental group 2), with DFDB alone(experimental group 3). Histologic analysis following 8 weeks of healing revealed the following results: 1. The lengths of connective tissue adhesion was 1.05±0.48mm in the control, 1.30±0.67mm in the test group I, 0.97±0.22mm in the test group II and 0.93±0.15mm in the test group III. There was no statistical significance between control and all experimental groups. 2. Changes in alveolar bone level was 0.97±0.27mm in the control group, 1.45±0.42mm in the test group I, 2.00±0.33mm in the test group II , 1.88±0.34mm in the test group III. There was no statistically significant difference between control and experimental group I. There was a statistically significant difference between the control and experimental group II,III.(p<0.05). There was no statistically significant difference between all experimental group. 3. Cementum formation was 1.13±0.17mm in the control, 1.78±0.31mm in the test group I, 2.17±0.38mm in the test group II, 2.15±0.47mm in the test group III with statistically significant differences between control group and all experimental group(P<0.05). There was no statistically significant differences between all experimental group. These results suggest that the use of composit graft of 50% calcium sulfate and 50% DFDB and DFDB alone in angulated 1 wall intrabony defects has little effects on connective tissue adhesion, but has significant effects on new bone and new cementum formations.