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Technicon Immuno I에 대한 평가

Other Titles
 Evaluation of the Technicon Immuno I Immunoassay System 
Authors
 김영아  ;  임재균  ;  임환섭  ;  이정운  ;  김정호  ;  권오헌 
Citation
 Korean Journal of Clinical Pathology (대한임상병리학회지), Vol.18(4) : 534-539, 1998 
Journal Title
 Korean Journal of Clinical Pathology (대한임상병리학회지) 
ISSN
 1015-6445 
Issue Date
1998
Abstract
Background :The Technicon Immuno I utilizes various enzymatic kinetic analysis with colorimetric detection and magnetic particles. We evaluated this fully automated random-access immunoassay system which can perform latex agglutination and magnetic-separation sandwich/competitive immunoassay. Method :We evaluated the assay precision, lower limits of detection, linearity, recovery, sample to sample carry-over, analytical interferences and comparison with other various methods for the following analytes: thyroxine (T4), thyroid stimulating hormone (TSH), free thyroxine (FT4), luteinizing hormone (LH), follicular stimulating hormone (FSH), prostate specific antigen (PSA), o-fetoprotein (AFP), carcino-embryonic antigen (CEA), CA 19-9, and digoxin. Result :Satisfactory results were obtained for within-run and between-day precision in most analytes. Lower limits of detection were slightly higher than claimed by the manufacturer. The linearity was acceptable, but there were proportional errors for CEA and FT4. The recovery rates were also good except for PSA. Sample to sample carry-over was not detected. No significant analytical interference was caused by hemoglobin (up to 2,000 mg/L), lipid (up to 85 mmol/L) and bilirubin (up to 325 pmol/L) except for digoxin, FT4 and PSA. The Technicon lmmuno I assay correlated well with the comparison methods in most analytes, but the proportional biases were found for PSA and LH. Conclusion :The Technicon lmmuno I is a satisfactory system for clinical use in most cases but more study would be requried for FT4. Especially, this system can replace the radioimmunoassay for FSH and LH.
Files in This Item:
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Jeong Ho(김정호) ORCID logo https://orcid.org/0000-0003-2479-0548
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/177126
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