Korean Nationwide surveillance of antimicrobial resistance of bacteria in 1997
Authors
Yunsop Chong ; Kyungwon Lee ; Yeon Joon Park ; Dong Seok Jeon ; Myung Hee Lee ; Moon Yeun Kim ; Chul Hun Chang ; Eui Chong Kim ; Nam Yong Lee ; Hyon Suk Kim ; Eun Suk Kang ; Hyun Chan Cho ; In Ki Paik ; Hye Soo Lee ; Sook Jin Jang ; Ae Ja Park ; Young Joo Cha ; Sung Ha Kang ; Myung Hee Lee ; Wonkeun Song ; Jong Hee Shin
Bacterial Physiological Phenomena* ; Drug Resistance, Microbial* ; Hospitals ; Humans ; Korea ; Microbial Sensitivity Tests ; Prevalence
Abstract
Antimicrobial-resistant bacteria are known to be prevalent in tertiary-care hospitals in Korea. Twenty hospitals participated to this surveillance to determine the nationwide prevalence of resistance bacteria in 1997. Seven per cent and 26% of Escherichia coli and Klebsiella pneumoniae were resistant to 3rd-generation cephalosporin. Increased resistance rates, 19% of Acinetobacter baumannii to ampicillin/sulbactam, and 17% of Pseudomonas aeruginoa to imipenem, were noted. The resistance rate to fluoroquinolone rose to 24% in E. coli, 56% in A. baumannii and 42% in P. aeruginosa. Mean resistance rates were similar in all hospital groups: about 17% of P. aeruginosa to imipenem, 50% of Haemophilus influenzae to ampicillin, 70% of Staphylococcus aureus to methicillin, and 70% of pneumococci to penicillin. In conclusion, nosocomial pathogens and problem resistant organisms are prevalent in smaller hospitals too, indicating nosocomial spread is a significant cause of the increasing prevalence of resistant bacteria in Korea.