0 4

Cited 0 times in

정신분열병 치료효과에 대한 신경인지기능의 예측력에 관한 연구

Other Titles
 Predictability of Neurocognitive Functions on the Treatment Effect in Schizophrenia. 
 오병훈  ;  조현상  ;  유계준  ;  이희상  ;  현명호  ;  최의헌 
 Journal of the Korean Neuropsychiatric Association (신경정신의학), Vol.37(6) : 1065-1073, 1998 
Journal Title
 Journal of the Korean Neuropsychiatric Association (신경정신의학) 
Issue Date
Objectives: This study was to investigate a wider range of neurocognitive function tests to find out how accurately each subtest could predict the outcomes of treatment in schizophrenics. Methods: The subjects were 33 inpatients diagnosed as schizophrenia according to DSM-IV. Each subject had a drug wash-out period of at least 1 week, and had been given K-WAIS, WMS-R, and Signal Detection, Decision Reaction Timer, and Motor Performance Series in Vienna Test System just before drug administration. Treatment response was evaluated with BPRS and CGI scales before and 8 weeks after drug treatment. We divided the subjects into responders and non-responders according to the outcomes of the above clinical scales in week 8. The responder group was defined with having 20% increase in BPRS score and a CGI score of less than 3. Then we compared the neuropsychological test results between the two groups. Results: Significantly different results between responders and non-responders were Verbal IQ and Full Scale IQ in K-WAIS, the number of correct responses in Signal Detection and Decision Reaction Timer in Vienna Test System. In discrimination analysis of the two groups using these subtests as variables, we could predict the responders with 66.7% accuracy, even though statistically non-significant. Conclusion: Although discriminating between responders and non-responders using neurocognitive function tests were proven to be statistically non-significant, the possibility that neurocognitive function tests can be utilized to predict the treatment outcome in schizophrenia cannot be completely ruled out.
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Psychiatry (정신과학교실) > 1. Journal Papers
Yonsei Authors
Oh, Byong Hoon(오병훈)
Cho, Hyun Sang(조현상) ORCID logo https://orcid.org/0000-0003-1019-9941
사서에게 알리기


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.