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TGF-β2 및 bFGF 망막색소상피세포 증식에 미치는 영향

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dc.contributor.author권오웅-
dc.date.accessioned2020-07-02T17:08:44Z-
dc.date.available2020-07-02T17:08:44Z-
dc.date.issued1998-
dc.identifier.issn0378-6471-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/176620-
dc.description.abstractThis study was undertaken to document the effect of transforming growth factor-β2 ( TGF-β2(TGF-β2) and basic fibroblast growth factor (bFGF) on the proliferation of pig retinal pigment epithelial cells (RPE). Whereas bFGF increased the proliferation, TGF-β2 showed the inhibitory effect on the proliferation The inhibitory effect of TGF-β2 disappeared in RPE subcultured with 10ng/ml of bFGF. Both TGF-β2- and bFGF-specific antisense oligonucleotides blocked the autocrine effect of the growth factors. PLC-71 -specific antisense oligonucleotide inhibited the effect of TGF-β2 and bFGF. Genistein inhibited the effect of TGF-β2 and bFGF in dose-dependent man, ner. The data suggest the involvement. of in PLC-/1 and tyrosine kinase in signalling-
dc.description.statementOfResponsibilityopen-
dc.languageKorean-
dc.publisher대한안과학회-
dc.relation.isPartOfJournal of the Korean Ophthalmological Society (대한안과학회지)-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleTGF-β2 및 bFGF 망막색소상피세포 증식에 미치는 영향-
dc.title.alternativeThe Effects of TGF-β2 and bFGF on the Proliferation of Retinal Pigment Epithelial Cells-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Ophthalmology (안과학교실)-
dc.contributor.googleauthor윤희성-
dc.contributor.googleauthor노세현-
dc.contributor.googleauthor이성철-
dc.contributor.googleauthor정진희-
dc.contributor.googleauthor유영현-
dc.contributor.localIdA00235-
dc.relation.journalcodeJ01838-
dc.identifier.eissn2092-9374-
dc.contributor.alternativeNameKwon, Oh Woong-
dc.contributor.affiliatedAuthor권오웅-
dc.citation.volume36-
dc.citation.number9-
dc.citation.startPage1192-
dc.citation.endPage1203-
dc.identifier.bibliographicCitationJournal of the Korean Ophthalmological Society (대한안과학회지), Vol.36(9) : 1192-1203, 1998-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers

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