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고위험 포상기태 환자에서 조기 항암화학요법 투여에 대한 임상적 연구

Other Titles
 A Clinical Study of Early Chemotherapy in High Risk Hydatidiform Mole Patients 
 송희영  ;  김재훈  ;  박동춘  ;  유영옥  ;  배석년  ;  김대훈  ;  김승조  ;  남궁성은 
 Korean Journal of Obstetrics and Gynecology (대한산부인과학회잡지), Vol.41(7) : 1839-1843, 1998 
Journal Title
 Korean Journal of Obstetrics and Gynecology (대한산부인과학회잡지) 
Issue Date
1616 hydatidiform mole (HM) patients have been treated in Korean Research Institude of Trophoblastic disease for the past twenty four years. These patients were divided into two groups, high risk and low risk group in accordance with the scoring system of Catholic University Medical colleage consisted of several factors such as age, gravity, hCG, mole type and uterine size. After evacuating mole, the overall remission rate was 76% and meanwhile, remission rate of high risk group was 69.2%. 31 out of 121 patients of high risk group were treated with early chemotherapy. In comparison with untreated group, data explained that the treated group with early chemotherapy needed less number of chemotherapy until complete remission (5.4±5.6 weeks versus 8.3±6.4 weeks p=0.0155). Further explained that the duration of chemotherapy for the treated group was shorter than that of the untreated group (16±23.93 weeks, versus 21.00±18.14 weeks p=0.335). Also, the statistics showed remarkable difference in the morbidity of disease (treated patient group with early chemotherapy 23.3±21.2 weeks versus untreated patient group 35.8±37.6, p=0.0346). In conclusion, early chemotherapy can reduce the duration of morbidity and numbers of chemotherapy.
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1. College of Medicine (의과대학) > Dept. of Obstetrics and Gynecology (산부인과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Jae Hoon(김재훈) ORCID logo https://orcid.org/0000-0001-6599-7065
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