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슬관절경 시술 후 관절강내 모르핀 투여 효과

Other Titles
 Intra-articular Morphine for Pain Relief after Arthroscopic Knee Surgery 
 배선준  ;  조범준  ;  남순호  ;  이행철  ;  안은경 
 Journal of Korean Society of Anesthesiologist (대한마취과학회지), Vol.35(1) : 120-124, 1998 
Journal Title
 Journal of Korean Society of Anesthesiologist (대한마취과학회지) 
Issue Date
Background: Opioids can produce potent antinociceptive effects by interacting with local opioid receptors in inflamed peripheral tissue. However, reports on pain relief with intra-articular morphine after arthroscopic knee operations are conflicting. In this study we examined the analgesic effects of the intraarticular administration of morphine after knee surgery. Methods: In a double-blind, randomized trial, we studied 26 patients who had received one of two injections at the end of surgery. The patients in group M(n=11) received 3 mg of morphine intraarticularly; those in group P(n=15), saline 20 ml intraarticularly as a placebo. Results: Patients in the morphine group had significantly lower pain scores throughout the 24-h postoperative period compared with those in the placebo group(P<0.05). There was less requirement for supplementary analgesics in the morphine group. Conclusions: Low doses of intraarticular morphine can significantly reduce pain after knee surgery without any systemic side effect.
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1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers
Yonsei Authors
Nam, Soon Ho(남순호)
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