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후신경아세포종 5례의 치료성적

Other Titles
 Treatment Outcomes of Olfactory Neuroblastoma: A Report of 5 Cases. 
 윤주헌  ;  김성식  ;  최영준  ;  김경수  ;  김영호 
 Korean Journal of Otolaryngology (대한이비인후과학회지), Vol.41(12) : 1562-1566, 1998 
Journal Title
 Korean Journal of Otolaryngology (대한이비인후과학회지) 
Issue Date
Background and Objectives:Several strategies have been reported for the treatment of olfactory neuroblastoma such as radiation therapy, chemotherapy, craniofacial resection, or their combination. However, a consensus regarding the optimal management has not been obtained. In this study, we examined the outcomes of different treatment modalities in five patients with olfactory neuroblastoma. Material and Method:Five patients diagnosed as olfactory neuroblastoma during the past 10 years were retrospectively analyzed. Results:Five patients were categorized by the modified Kadish's staging system. Three patients underwent surgery. Radiotherapy was given concurrently with chemotherapy for two patients. Distant metastases were observed in two cases, one in the heart and the other in the cervical lymph node. After a median follow-up of 34 (12-87) months, two patients who underwent craniofacial resection only and another two patients who received combined radiotherapy and chemotherapy are still alive. One patient who underwent Denker's operation with postoperative radiotherapy had died of heart failure as a result of cardiac metastasis. Conclusion:We suggest a complete surgical resection as a primary treatment modality, however, a multi-drug chemotherapy with radiotherapy could be the choice of treatment in cases of children or one with distant metastasis.
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1. College of Medicine (의과대학) > Dept. of Otorhinolaryngology (이비인후과학교실) > 1. Journal Papers
Yonsei Authors
Yoon, Joo Heon(윤주헌)
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