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지속성 외래 복막 투석 환자에서 경구 영양 음료 투여에 의한 영양 보충의 효과

Other Titles
 The Effect of Oral Nutritional Supplement in Malnourished CAPD Patients 
 이인희  ;  강신욱  ;  노현진  ;  신석균  ;  최규헌  ;  하성규  ;  아호영  ;  한대석  ;  이승민  ;  조은영  ;  이종호 
 Korean Journal of Nephrology (대한신장학회지), Vol.17(2) : 299-310, 1998 
Journal Title
 Korean Journal of Nephrology (대한신장학회지) 
Issue Date
Protein-calorie malnutrition is common in CAPD patients and is associated with increased morbidity and moitality. To evaluate the effect of an oral nutritional supplement(Greenbia RD, DR. CHUNGS FOOD CO., LTD, Seoul, Korea) providing 800Cal and 24g of protein daily in addition to their usual diet on the nutritional status, we conducted a prospective study in malnourished CAPD patients (N=26). Subjects were randomised into 2 groups' group I(N=15) taking Greenbia RD" for 3 months, group II(N=11) as control. In group I, the data of 12 patients who completed the 3-months study period were analyzed. There were no statistically significant changes in biochemical parameters including total protein, serum albumin, prealbumin, transfemn during the study period in both groups, but IGF-I increased significantly in group I (129.2± 88.8 vs. 174.1± 109.3ng/mL, P<0.05). Total calorie (1349±272 vs. 1720±251CaVday, P<0.05) and protein intake(1.05±0.29 vs. 1.2±40.25g/kg/day, P<0.05) as- sessed by 72-hours dietary recall method increased significantly in group I with oral supplement. Body weight(52.4±8.3 vs. 54.2±8.8kg, P<O.05), body mass index(18.7±1.8 vs. 19.5±2.0kg/m', P<0.05), % body fat(13.2±4.2 vs. 15.4±3.9%, P<0.05), total body mus- cle(16.8±3.7 vs. 18.2±3.3kg, P<0.05), midarm cir- cumference(22.8±2.1 vs. 23.7±2.2cm, P<0.05) and calculated arm muscle area(25.9±7.1 vs. 28.9±6.1 cm, P<0.05) increased significantly in group I after 3 months. Biceps and triceps skinfold thickness tended to increase following oral nutritional supple- ment but there was no statistical significance. Anthropometric parameters remained unchanged in group II. Kt/Vurea, normalized protein catabolic rate and standardized creatinine clearance did not change in both groups. In conclusion, oral nutritional supple- ment in malnourished CAPD patients well tolerated and was effective in improving the anthropometric parameters.
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1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Choi, Kyu Hun(최규헌) ORCID logo https://orcid.org/0000-0003-0095-9011
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