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고관절 치환술을 받는 환자에서 Ketorolac Tromethamine 정주에 의한 선행진통 효과

Other Titles
 The Effects of Preemptive Intravenous Ketorolac for Total Hip Replacement Patients 
 배선준  ;  남순호  ;  이윤우  ;  남용택  ;  김원주 
 Journal of Korean Society of Anesthesiologist (대한마취과학회지), Vol.35(3) : 511-517, 1998 
Journal Title
 Journal of Korean Society of Anesthesiologist (대한마취과학회지) 
Issue Date
Background: The purpose of this study is to examine the effect of intravenous ketorolac administration before surgical stimulation for postoperative pain control. Methods: Forty four patients scheduled for total hip replacement were randomly assigned to one of three groups of prospectively designed study. Group 1(n=14) received intravenous saline(placebo) and Group 2(n=15) received intravenous ketorolac(30 mg) at one hour after skin incision and Group 3(n=15) received intravenous ketorolac(30 mg) before induction. Postoperative pain relief was provided with intravenous morphine from PCA system. Postoperative visual analogue pain score(VAS), analgesic requirement and side effects were evaluated and compared between groups for postoperative two days. Results: VAS at rest were significantly less in Group 2,3 than in Group 1 at 3 hours after surgery(p<0.05) and significantly less in group 3 than in group 1 at 6 and 9 hours after surgery(p<0.05). VAS on movement were significantly less in group 3 than group 1 at 1 hour and significantly less in group 2,3 than group 1 at 3 and 6 hours after surgery(p<0.05). Patient controlled morphine consumption in group 1 was significantly higher than in group 2,3 for 12 hours after surgery. After administration of intravenous ketorolac any side effect did not occur. Conclusions: Administration of intravenous ketorolac before skin incision as a pre-emptive analgesia has better analgesia than those of 1 hour after skin incision and no administration of ketorolac.
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1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers
Yonsei Authors
Nam, Soon Ho(남순호)
Nam, Yong Taek(남용택)
Bai, Sun Joon(배선준) ORCID logo https://orcid.org/0000-0001-5027-3232
Lee, Youn Woo(이윤우)
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