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비인강암의 3차원 입체조형치료에서 등가선량분포에 관한 연구

Other Titles
 3-Dimensional Conformal Radiation Therapy in Carcinoma of The Nasopharynx 
 금기창  ;  김귀언  ;  이상훈  ;  장세경  ;  임지훈  ;  박원  ;  서창옥 
 Journal of the Korean Society of Therapeutics Radiology (대한치료방사선과학회지), Vol.16(4) : 399-408, 1998 
Journal Title
 Journal of the Korean Society of Therapeutics Radiology (대한치료방사선과학회지) 
Issue Date
Purpose : This study was designed to demonstrate the potential therapeutic advantage of 3-dimensional (3-D) treatment planning over the conventional 2-dimensional (2-D) approach in patients with carcinoma of the nasopharynx. Materials and Methods : The two techniques were compared both qualitatively and quantitatively for the boost portion of the treatment (19.8 Gy of a total 70.2 Gy treatment schedule) in patient with T4. The comparisons between 2-D and 3-D plans were made using dose statistics, dose-volume histogram, tumor control probabilities, and normal tissue complication probabilities. Results : The 3-D treatment planning improved the dose homogeneity in the planning target volume. In addition, it caused the mean dose of the planning target volume to increase by 15.2% over 2-D planning. The mean dose to normal structures such as the temporal lobe, brain stem, parotid gland, and temporomandibular joint was reduced with the 3-D plan. The probability of tumor control was increased by 6% with 3-D treatment planning compared to the 2-D planning, while the probability of normal tissue complication was reduced. Conclusion : This study demonstrated the potential advantage of increasing the tumor control by using 3-D planning. but prospective studies are required to define the true clinical benefit.
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1. College of Medicine (의과대학) > Dept. of Radiation Oncology (방사선종양학교실) > 1. Journal Papers
Yonsei Authors
Keum, Ki Chang(금기창) ORCID logo https://orcid.org/0000-0003-4123-7998
Suh, Chang Ok(서창옥)
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