Acantholytic dyskeratotic epidermal nevus induced by ultraviolet B radiation

Abstract

We report a case of acantholytic dyskeratotic epidermal nevus induced by repeated ultraviolet B radiation in a 16-year-old Korean girl. She had experienced pruritic skin rashes on the right side of the abdomen and flank area in a zosteriform distribution for the past 10 years. They were aggravated during the summer and spontaneously disappeared in the winter. Papules revealed acantholytic dyskeratotic cells that were diagnosed as acantholytic dyskeratotic epidermal nevus. Suberythemal and erythemal doses of UVB were irradiated to the lesional skin (right side of abdomen) and nonlesional skin (left side of abdomen) for 4 consecutive days. UVB-induced pruritic papules were observed on the lesional skin and a biopsy specimen of the papules also showed acantholytic dyskeratotic cells, which were compatible with acantholytic dyskeratotic epidermal nevus.