Secondary amyloidosis, a serious complication of chronic inflammatory disease, is caused by the deposition of amyloid fibrils in various organs. Because of the decrease in chronic infectious disease due to the use of antibiotice, rheumatoid arhhritis has become the most common disease which induces secondary and systemci amyloidosis. We had experienced a case of reactive systemic amyloidosis associated with rheumatoid arthritis especially involving heart and kidney, confirmed by renal biopsy and endomyocardial biopsy. This case was AA type amyloid confirmed by method of permanganate reaction.