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감염관련 혈구탐식증후군 (Infection-Associated Hemophagocytic Syndrome)으로 추정되는 2예 보고 및 국내 증례 분석

Other Titles
 Two Cases of Infection-associated Hemophagocytic Syndrome with Review of Literature 
 류동렬  ;  염준섭  ;  장경희  ;  홍성관  ;  박윤수  ;  최영화  ;  송영구  ;  유내춘  ;  한지숙 
 Korean Journal of Infectious Diseases (감염), Vol.30(5) : 470-477, 1998 
Journal Title
 Korean Journal of Infectious Diseases (감염) 
Issue Date
The hemophagocytic syndrome is a disorder caused by systemic proliferation of benign histiocytes with avid phagocytosis of blood cells. Although this is an established disease entity, early clinical diagnosis is often difficult. The disease is known to be rare. The clinical and laboratory characteristics of 33 patients with the infection-associated hemophagocytic syndrome were reviewed which included previously reported 31 cases from the literature, and 2 recent cases presented in this study. The patients were 22 males and 11 females with a mean age of 20.8 years(range 1 to 69 years). Ten patients were associated with viral infection and seven with bacterial infection. The infection usually occurs in patients with preexisting immunological abnormalities, but in this study underlying illness was found in only 8 out of the 33 cases. The overall mortality rate was 63.6%, which is a higher percentage than in other countries. Since the clinical course can be fulminant, accurate diagnosis and effective treatment are needed.
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kim, June Myung(김준명)
Song, Young Goo(송영구) ORCID logo https://orcid.org/0000-0002-0733-4156
Yoo, Nae Choon(유내춘)
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