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Comparative study of bentiromide test and endoscopic retrograde pancreatography in patients with chronic pancreatitis

Authors
 Jae Bock Chung  ;  Seung Woo Park  ;  Si Young Song  ;  Young Myung Moon  ;  Jin Kyung Kang  ;  In Suh Park 
Citation
 YONSEI MEDICAL JOURNAL, Vol.39(1) : 45-49, 1998 
Journal Title
 YONSEI MEDICAL JOURNAL 
ISSN
 0513-5796 
Issue Date
1998
MeSH
4-Aminobenzoic Acid ; Adult ; Aged ; Bicarbonates/metabolism ; Chronic Disease ; Female ; Humans ; Male ; Middle Aged ; Pancreas/diagnostic imaging* ; Pancreatitis/diagnosis* ; Radiography ; para-Aminobenzoates*
Abstract
We performed a bentiromide test in 25 patients with chronic pancreatitis and 7 normal controls to evaluate pancreatic exocrine function, and compared the test results of patients with their endoscopic retrograde pancreatography(ERP) findings. The cumulative 6-hour recovery rate of para-aminobenzoic acid(PABA) in the urine was significantly lower in patients with chronic pancreatitis(55.8 ± 24.2%) than in controls(82.0 ± 10.0%). Among 25 patients with chronic pancreatitis, however, 7 patients showed normal recovery rates of PABA. Pancreatograms of the patients represented 4 mild changes, 5 moderate changes, and 16 marked changes. The average 6-hour recovery rates of PABA of the groups were 56.9 ± 21.6%, 78.4 ± 10.5%, and 47.2 ± 23.7%, respectively. Urinary PABA recovery rates were found subnormal as follows: 3(75%) in the mild changes group; 1(20%) in the moderate changes group; and 14(87.5%) in the marked changes group. We found hardly any correlation between the degree of functional impairment and the changes noted by ERP. These findings suggest that both the pancreatic function test and morphologic study are required to evaluate the degree of functional impairment in patients with chronic pancreatitis.
Files in This Item:
T199800397.pdf Download
DOI
10.3349/ymj.1998.39.1.45
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Park, Seung Woo(박승우) ORCID logo https://orcid.org/0000-0001-8230-964X
Song, Si Young(송시영) ORCID logo https://orcid.org/0000-0002-1417-4314
Chung, Jae Bock(정재복)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/176293
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