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A National Consensus Survey for Current Practice in Brain Tumor Management III: Brain Metastasis and Primary Central Nervous System Lymphoma

 Sung Kwon Kim  ;  Ji Eun Park  ;  Kyung Hwan Kim  ;  Jin Mo Cho  ;  Jangsup Moon  ;  Wan Soo Yoon  ;  Se Hoon Kim  ;  Young Il Kim  ;  Young Zoon Kim  ;  Ho Sung Kim  ;  Yun Sik Dho  ;  Jae Sung Park  ;  Hong In Yoon  ;  Youngbeom Seo  ;  Kyoung Su Sung  ;  Jin Ho Song  ;  Chan Woo Wee  ;  Se Hoon Lee  ;  Do Hoon Lim  ;  Jung Ho Im  ;  Jong Hee Chang  ;  Myung Hoon Han  ;  Je Beom Hong  ;  Kihwan Hwang  ;  Chul Kee Park  ;  Youn Soo Lee  ;  Ho Shin Gwak  ;  KSNO Guideline Working Group 
 Brain Tumor Research and Treatment, Vol.8(1) : 20-28, 2020-04 
Journal Title
 Brain Tumor Research and Treatment 
Issue Date
Brain tumors ; Korean Society for Neuro-Oncology ; Lymphoma, Guideline Working Group ; Metastasis ; Practice patterns
Background: The Guideline Working Group of the Korean Society for Neuro-Oncology (KSNO) conducted the nationwide questionnaire survey for diverse queries facing to treat patients with brain tumor. As part III of the survey, the aim of this study is to evaluate the national patterns of clinical practice for patients with brain metastasis and primary central nervous system lymphoma (PCNSL). Methods: A web-based survey was sent to all members of the KSNO by email. The survey included 7 questions of brain metastasis and 5 questions of PCNSL, focused on the management strategies in specific situations. All questions were developed by consensus of the Guideline Working Group. Results: In the survey about brain metastasis, respondents preferred surgical resection with adjuvant treatment for patients with a surgically accessible single brain metastatic lesion less than 3 cm in size without extracranial systemic lesions. However, most respondents considered radiosurgery for surgically inaccessible lesions. As the preferred treatment of multiple brain metastases according to the number of brain lesions, respondents tended to choose radiotherapy with increasing number of lesions. Radiosurgery was mostly chosen for the brain metastases of less than or equal to 4. In the survey about PCNSL, a half of respondents choose high-dose methotrexate-based polychemotherapy as the first-line induction therapy for PCNSL. The consolidation and salvage therapy showed a little variation among respondents. For PCNSL patients with cerebrospinal fluid dissemination, intrathecal chemotherapy was most preferred. Conclusion: The survey demonstrates the prevailing clinical practice patterns for patients with brain metastasis and PCNSL among members of the KSNO. This information provides a point of reference for establishing a practical guideline in the management of brain metastasis and PCNSL.
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1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiation Oncology (방사선종양학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Neurosurgery (신경외과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Se Hoon(김세훈) ORCID logo https://orcid.org/0000-0001-7516-7372
Yoon, Hong In(윤홍인) ORCID logo https://orcid.org/0000-0002-2106-6856
Chang, Jong Hee(장종희) ORCID logo https://orcid.org/0000-0003-1509-9800
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