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Diagnosis of Renal Transplant Rejection: Banff Classification and Beyond

Authors
 Hyeon Joo Jeong 
Citation
 KIDNEY RESEARCH AND CLINICAL PRACTICE, Vol.39(1) : 17-31, 2020-03 
Journal Title
 KIDNEY RESEARCH AND CLINICAL PRACTICE 
ISSN
 2211-9132 
Issue Date
2020-03
Keywords
Banff classification ; Gene transcripts ; Morphology ; Rejection ; Renal transplantation
Abstract
Diagnosis of renal transplant rejection is dependent on interpretation of renal allograft biopsies. The Banff Classification of Allograft Pathology, which was developed as a standardized working classification system in 1991, has contributed to the standardization of definitions for histologic injuries resulting from renal allograft rejections and provided a universal grading system for assessing these injuries. It has also helped to provide insight into the underlying pathogenic mechanisms that contribute to transplant rejection. In addition to histological and immunologic parameters, molecular tools are now being used to facilitate the diagnosis of rejection. In this review, I will discuss morphologic features of renal transplant rejections as well as major revisions and pitfalls of the Banff classification system, and provide future perspectives.
Files in This Item:
T202001167.pdf Download
DOI
10.23876/j.krcp.20.003
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
Yonsei Authors
Jeong, Hyeon Joo(정현주) ORCID logo https://orcid.org/0000-0002-9695-1227
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/176002
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