Cited 15 times in
Incorporation of carboxybetaine methacrylate into poly(methyl methacrylate) to prevent multi-species biofilm formation
DC Field | Value | Language |
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dc.contributor.author | 권재성 | - |
dc.contributor.author | 최성환 | - |
dc.date.accessioned | 2020-06-17T00:28:49Z | - |
dc.date.available | 2020-06-17T00:28:49Z | - |
dc.date.issued | 2020-06 | - |
dc.identifier.issn | 1226-086X | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/175988 | - |
dc.description.abstract | Carboxybetaine methacrylate (CBMA), which has anti-biofouling properties, was incorporated into poly(methyl methacrylate) (PMMA) to prevent multi-species biofilm formation without impairing the critical mechanical properties of the PMMA. The incorporation of 2-methacryloyloxyethyl phosphorylcholine (MPC, 3 wt%) was used as a positive control. PMMA wettability was found to increase with increasing CBMA content. The addition of CBMA resulted in decreased mechanical properties of PMMA. The incorporation of 3% CBMA into PMMA resulted in considerable long-term anti-biofouling effects that reduce adhesion of various fungi, bacteria (Candida albicans, Actinomyces naeslundii, and Veillonella parvula), and a human saliva-derived biofilm. The anti-biofouling effect of CBMA-incorporated PMMA surpassed that of the positive control. By calculating the intensity of the collective band using Raman spectroscopy, CBMA was proven to form the most stable hydration layer. Neither CBMA nor MPC groups showed cytotoxicity. Occlusal splints fabricated using 3% CBMA showed clinically acceptable aesthetic properties with slight turbidity. Despite a limitation in terms of deteriorations of the mechanical properties, the addition of an appropriate amount of CBMA to PMMA inhibited the attachment of fungi and bacteria and suppressed multi-species biofilm growth. The aesthetic properties of CBMA-incorporated PMMA are acceptable for clinical practice. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Elsevier | - |
dc.relation.isPartOf | JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Incorporation of carboxybetaine methacrylate into poly(methyl methacrylate) to prevent multi-species biofilm formation | - |
dc.type | Article | - |
dc.contributor.college | College of Dentistry (치과대학) | - |
dc.contributor.department | Dept. of Dental Biomaterials and Bioengineering (치과생체재료공학교실) | - |
dc.contributor.googleauthor | Jie Jin | - |
dc.contributor.googleauthor | Ji-Yeong Kim | - |
dc.contributor.googleauthor | Woojin Choi | - |
dc.contributor.googleauthor | Myung-Jin Lee | - |
dc.contributor.googleauthor | Ji-Young Seo | - |
dc.contributor.googleauthor | Jaehun Yu | - |
dc.contributor.googleauthor | Jae-Sung Kwon | - |
dc.contributor.googleauthor | Jinkee Hong | - |
dc.contributor.googleauthor | Sung-Hwan Choi | - |
dc.identifier.doi | 10.1016/j.jiec.2020.03.003 | - |
dc.contributor.localId | A00247 | - |
dc.contributor.localId | A04083 | - |
dc.relation.journalcode | J03016 | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S1226086X20301210 | - |
dc.subject.keyword | Carboxybetaine methacrylate | - |
dc.subject.keyword | Poly(methyl methacrylate) | - |
dc.subject.keyword | Biofilm | - |
dc.subject.keyword | Anti-biofouling effects | - |
dc.subject.keyword | Occlusal splint | - |
dc.contributor.alternativeName | Kwon, Jae-Sung | - |
dc.contributor.affiliatedAuthor | 권재성 | - |
dc.contributor.affiliatedAuthor | 최성환 | - |
dc.citation.volume | 86 | - |
dc.citation.startPage | 194 | - |
dc.citation.endPage | 204 | - |
dc.identifier.bibliographicCitation | JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY, Vol.86 : 194-204, 2020-06 | - |
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