Management of migraine, one of common primary headache disorders, involves the diverse strategies non-pharmacological
treatment, such as headache diary, lifestyle modification, regular exercise and relaxation, cognitive behavioral therapy and
neurostimulation, and pharmacological treatment. Among the treatments, this review described a pharmacologic treatment of
migraine, classified into acute and preventive treatment based on the severity and the frequency of headache. It introduced the
way to optimize pharmacological treatment and updated the latest treatment for migraine.