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Generation of a human induced pluripotent stem cell line from a patient with Leber congenital amaurosis
DC Field | Value | Language |
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dc.contributor.author | 한진우 | - |
dc.date.accessioned | 2020-04-13T17:00:33Z | - |
dc.date.available | 2020-04-13T17:00:33Z | - |
dc.date.issued | 2020 | - |
dc.identifier.issn | 1873-5061 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/175613 | - |
dc.description.abstract | Leber congenital amaurosis (LCA) is an inherited retinal dystrophy that is characterized by severe visual impairment in early infancy. We generated a human induced pluripotent stem cell (hiPSC) line, DKHi090-A, from peripheral blood mononuclear cells (PBMCs) of a patient with LCA, by using a Sendai virus-based gene delivery system. We confirmed that DKHi090-A has a nicotinamide mononucleotide adenyltransferase 1 (NMNAT1) mutation and normal karyotype. DKHi090-A line is pluripotent and is capable of multilineage differentiation. This cell line is registered and is available at the National Stem Cell Bank, Korea National Institute of Health. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Elsevier | - |
dc.relation.isPartOf | STEM CELL RESEARCH | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Generation of a human induced pluripotent stem cell line from a patient with Leber congenital amaurosis | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Ophthalmology (안과학교실) | - |
dc.contributor.googleauthor | Hyeyeon Park | - |
dc.contributor.googleauthor | Jinu Han | - |
dc.contributor.googleauthor | Youngsun Lee | - |
dc.contributor.googleauthor | Sungwook Kwak | - |
dc.contributor.googleauthor | Soo Kyung Koo | - |
dc.identifier.doi | 10.1016/j.scr.2020.101725 | - |
dc.contributor.localId | A04329 | - |
dc.relation.journalcode | J02680 | - |
dc.identifier.eissn | 1876-7753 | - |
dc.identifier.pmid | 32036247 | - |
dc.contributor.alternativeName | Han, Jin U | - |
dc.contributor.affiliatedAuthor | 한진우 | - |
dc.citation.volume | 43 | - |
dc.citation.startPage | e101725 | - |
dc.identifier.bibliographicCitation | STEM CELL RESEARCH, Vol.43 : e101725, 2020 | - |
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