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Generation of a human induced pluripotent stem cell line from a patient with Leber congenital amaurosis

DC FieldValueLanguage
dc.contributor.author한진우-
dc.date.accessioned2020-04-13T17:00:33Z-
dc.date.available2020-04-13T17:00:33Z-
dc.date.issued2020-
dc.identifier.issn1873-5061-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/175613-
dc.description.abstractLeber congenital amaurosis (LCA) is an inherited retinal dystrophy that is characterized by severe visual impairment in early infancy. We generated a human induced pluripotent stem cell (hiPSC) line, DKHi090-A, from peripheral blood mononuclear cells (PBMCs) of a patient with LCA, by using a Sendai virus-based gene delivery system. We confirmed that DKHi090-A has a nicotinamide mononucleotide adenyltransferase 1 (NMNAT1) mutation and normal karyotype. DKHi090-A line is pluripotent and is capable of multilineage differentiation. This cell line is registered and is available at the National Stem Cell Bank, Korea National Institute of Health.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherElsevier-
dc.relation.isPartOfSTEM CELL RESEARCH-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleGeneration of a human induced pluripotent stem cell line from a patient with Leber congenital amaurosis-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Ophthalmology (안과학교실)-
dc.contributor.googleauthorHyeyeon Park-
dc.contributor.googleauthorJinu Han-
dc.contributor.googleauthorYoungsun Lee-
dc.contributor.googleauthorSungwook Kwak-
dc.contributor.googleauthorSoo Kyung Koo-
dc.identifier.doi10.1016/j.scr.2020.101725-
dc.contributor.localIdA04329-
dc.relation.journalcodeJ02680-
dc.identifier.eissn1876-7753-
dc.identifier.pmid32036247-
dc.contributor.alternativeNameHan, Jin U-
dc.contributor.affiliatedAuthor한진우-
dc.citation.volume43-
dc.citation.startPagee101725-
dc.identifier.bibliographicCitationSTEM CELL RESEARCH, Vol.43 : e101725, 2020-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers

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