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Diagnostic ability of vessel density measured by spectral-domain optical coherence tomography angiography for glaucoma in patients with high myopia

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dc.contributor.author김찬윤-
dc.contributor.author배형원-
dc.contributor.author성공제-
dc.contributor.author이광현-
dc.contributor.author이상엽-
dc.contributor.author최웅락-
dc.contributor.author배형원-
dc.contributor.author성공제-
dc.contributor.author이광현-
dc.contributor.author이상엽-
dc.contributor.author최웅락-
dc.date.accessioned2020-04-13T16:57:59Z-
dc.date.available2020-04-13T16:57:59Z-
dc.date.issued2020-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/175585-
dc.description.abstractAlthough early glaucoma detection is important to prevent visual loss due to disease progression, its clinical diagnosis in highly myopic eyes is still difficult. Many studies using optical coherence tomography (OCT) angiography (OCTA) reported decreased vessel density (VD) in glaucomatous eyes compared to normal eyes. We evaluated the diagnostic ability of peripapillary VD and macular VD measured by OCTA, comparing them with conventional valuables such as peripapillary retinal nerve fibre layer (RNFL) thickness and macular ganglion cell-inner plexiform layer (GCIPL) thickness measured by OCT. We also calculated the average VD ratio (VDR) (average outer macular VD/average inner macular VD), superior VDR (superior outer macular VD/average inner macular VD), and inferior VDR (inferior outer macular VD/average inner macular VD). Totally, 169 eyes from 169 subjects were enrolled. Among OCTA measurements, the best diagnostic parameters were average VDR (AUROC: 0.852 and 0.909) and inferior VDR (AUROC: 0.820 and 0.941) in nonhighly and highly myopic eyes, respectively. Inferior VDR showed better diagnostic ability than most of the other OCT measurements including peripapillary RNFL thickness and macular GCIPL thickness in highly myopic eyes. Accordingly, OCTA measurements can be useful for diagnosing glaucoma in highly myopic eyes, especially when using calculated indices such as average VDR or inferior VDR.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherNature Publishing Group-
dc.relation.isPartOfSCIENTIFIC REPORTS-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleDiagnostic ability of vessel density measured by spectral-domain optical coherence tomography angiography for glaucoma in patients with high myopia-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Ophthalmology (안과학교실)-
dc.contributor.googleauthorKwanghyun Lee-
dc.contributor.googleauthorKyung Joo Maeng-
dc.contributor.googleauthorJoo Yeon Kim-
dc.contributor.googleauthorHeon Yang-
dc.contributor.googleauthorWungrak Choi-
dc.contributor.googleauthorSang Yeop Lee-
dc.contributor.googleauthorGong Je Seong-
dc.contributor.googleauthorChan Yun Kim-
dc.contributor.googleauthorHyoung Won Bae-
dc.identifier.doi10.1038/s41598-020-60051-0-
dc.contributor.localIdA01035-
dc.contributor.localIdA01814-
dc.contributor.localIdA01814-
dc.contributor.localIdA01946-
dc.contributor.localIdA01946-
dc.contributor.localIdA04994-
dc.contributor.localIdA04994-
dc.contributor.localIdA02820-
dc.contributor.localIdA02820-
dc.contributor.localIdA04123-
dc.contributor.localIdA04123-
dc.contributor.localIdA01814-
dc.contributor.localIdA01814-
dc.contributor.localIdA01946-
dc.contributor.localIdA01946-
dc.contributor.localIdA04994-
dc.contributor.localIdA04994-
dc.contributor.localIdA02820-
dc.contributor.localIdA02820-
dc.contributor.localIdA04123-
dc.contributor.localIdA04123-
dc.relation.journalcodeJ02646-
dc.identifier.eissn2045-2322-
dc.identifier.pmid32080343-
dc.contributor.alternativeNameKim, Chan Yun-
dc.contributor.affiliatedAuthor김찬윤-
dc.contributor.affiliatedAuthor배형원-
dc.contributor.affiliatedAuthor배형원-
dc.contributor.affiliatedAuthor성공제-
dc.contributor.affiliatedAuthor성공제-
dc.contributor.affiliatedAuthor이광현-
dc.contributor.affiliatedAuthor이광현-
dc.contributor.affiliatedAuthor이상엽-
dc.contributor.affiliatedAuthor이상엽-
dc.contributor.affiliatedAuthor최웅락-
dc.contributor.affiliatedAuthor최웅락-
dc.contributor.affiliatedAuthor배형원-
dc.contributor.affiliatedAuthor배형원-
dc.contributor.affiliatedAuthor성공제-
dc.contributor.affiliatedAuthor성공제-
dc.contributor.affiliatedAuthor이광현-
dc.contributor.affiliatedAuthor이광현-
dc.contributor.affiliatedAuthor이상엽-
dc.contributor.affiliatedAuthor이상엽-
dc.contributor.affiliatedAuthor최웅락-
dc.contributor.affiliatedAuthor최웅락-
dc.citation.volume10-
dc.citation.number1-
dc.citation.startPagee3027-
dc.identifier.bibliographicCitationSCIENTIFIC REPORTS, Vol.10(1) : e3027, 2020-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers

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