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비분절형 백반증 환자의 노출부위 탈색소반에서 발생한 다발성 광선각화증

Other Titles
 Multiple Actinic Keratoses within Vitiliginous Patches in a Patient with Non-segmental Vitiligo 
 신재용  ;  김도영  ;  박수진  ;  구자승  ;  한승경  ;  오상호 
 Korean Journal of Dermatology (대한피부과학회지), Vol.58(1) : 39-42, 2020 
Journal Title
 Korean Journal of Dermatology (대한피부과학회지) 
Issue Date
Actinic keratosis ; Skin cancer ; Vitiligo ; UV
A 74-year-old man visited our department with complaints of multiple asymptomatic erythematous scaly crusted patches on the scalp. He had non-segmental vitiligo with the extent of over 20% of the body surface area for 30 years. Biopsies showed hyperkeratosis, foci of atypical, pleomorphic keratinocytes along the basal cell layer, and marked solar elastosis, consistent with actinic keratosis (AK). Melan-A and Fontana-Masson staining showed absence of melanin and melanocytes. Despite conflicting data on the prevalence of skin cancers in patients with vitiligo, it is known that vitiligo does not increase nor decrease the risk of skin cancer. Recent studies have reported that patients with vitiligo lesions show increased epidermal expression of wild-type p53 protein than healthy controls. However, a few cases of skin cancer have been reported in patients with vitiligo. Here, we report a case of AK developing in vitiligo lesions. Dermatologists should not overlook the possible occurrence of AK or skin cancers in sun-exposed vitiliginous skin.
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Dermatology (피부과학교실) > 1. Journal Papers
Yonsei Authors
Koo, Ja Seung(구자승) ORCID logo https://orcid.org/0000-0003-4546-4709
Kim, Do Young(김도영) ORCID logo https://orcid.org/0000-0002-0194-9854
Oh, Sang Ho(오상호) ORCID logo https://orcid.org/0000-0002-4477-1400
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