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Recent clinical applications of external beam radiotherapy for hepatocellular carcinoma according to guidelines, major trials and meta-analyses

Authors
 Chai Hong Rim  ;  Hyung Joon Yim  ;  Sunmin Park  ;  Jinsil Seong 
Citation
 JOURNAL OF MEDICAL IMAGING AND RADIATION ONCOLOGY, Vol.63(6) : 812-821, 2019 
Journal Title
 JOURNAL OF MEDICAL IMAGING AND RADIATION ONCOLOGY 
ISSN
 1754-9477 
Issue Date
2019
Keywords
external beam radiotherapy ; guidelines ; hepatocellular carcinoma ; liver neoplasm ; radiation therapy
Abstract
External beam radiotherapy (EBRT) for hepatocellular carcinoma (HCC) has not been widely used due to lack of high-level evidence, despite its potent local therapeutic effect. While clinical evidence has accumulated and meta-analyses of observational studies have provided integrated information to help in clinical decision-making, a recent randomized trial demonstrated the benefit of EBRT in cases of HCC with major vessel invasion. Based on these trends, the efficacy of EBRT has been better recognized, and EBRT has been more frequently recommended in several international treatment guidelines newly updated in 2018. This review examined the key issues of EBRT in the guidelines updated in 2018 as well as recently published noteworthy randomized trials and meta-analyses. Ongoing trials to identify the trends and direction of future research on EBRT for HCC were also reviewed.
Full Text
https://onlinelibrary.wiley.com/doi/full/10.1111/1754-9485.12948
DOI
10.1111/1754-9485.12948
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiation Oncology (방사선종양학교실) > 1. Journal Papers
Yonsei Authors
Seong, Jin Sil(성진실) ORCID logo https://orcid.org/0000-0003-1794-5951
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/175177
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