Cited 17 times in
Anemia in Association with Cognitive Impairment: A Systematic Review and Meta-Analysis
DC Field | Value | Language |
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dc.contributor.author | 박병진 | - |
dc.contributor.author | 심재용 | - |
dc.date.accessioned | 2020-02-11T06:43:53Z | - |
dc.date.available | 2020-02-11T06:43:53Z | - |
dc.date.issued | 2019 | - |
dc.identifier.issn | 1387-2877 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/174805 | - |
dc.description.abstract | BACKGROUND: Prevalence of both anemia and cognitive impairment tends to increase with age. Individual studies have recently shown that anemia could be associated with cognitive impairment. OBJECTIVE: To investigate the association between anemia and cognitive impairment including dementia. METHODS: Two of the authors systematically searched PubMed, EMBASE, and the Cochrane library to retrieve observational studies reporting a relationship between anemia and cognitive impairment from 1964 to July 10, 2019. Case-control and cohort studies were included, and odds ratios (ORs) or relative risks (RRs) with 95% confidence intervals (CIs) for the risk of cognitive impairment were calculated using a random-effects model. RESULTS: In total, 16 observational studies including eight case-control studies and eight cohort studies were included in the final analysis. Anemia was significantly linked to cognitive impairment (OR or RR 1.51; 95% CI: 1.32-1.73) in a random-effects meta-analysis, albeit with medium heterogeneity (I2 = 47.8%). Meta-estimates of dementia from prospective population-based cohort studies were similar (RR 1.46; 95% CI: 1.22-1.76) without substantial heterogeneity (I2 = 23.2%). CONCLUSION: Our meta-analysis indicates that anemia is associated with cognitive impairment. Further prospective research is warranted to determine the cause-effect relationship of anemia with cognitive impairment and whether treatment of anemia might reduce the risk of dementia. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | IOS Press | - |
dc.relation.isPartOf | Journal of Alzheimers Disease | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Anemia in Association with Cognitive Impairment: A Systematic Review and Meta-Analysis | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Family Medicine (가정의학교실) | - |
dc.contributor.googleauthor | Kim, Hong-Bae | - |
dc.contributor.googleauthor | Park, Byoungjin | - |
dc.contributor.googleauthor | Shim, Jae-Yong | - |
dc.identifier.doi | 10.3233/JAD-190521 | - |
dc.contributor.localId | A01477 | - |
dc.contributor.localId | A02207 | - |
dc.relation.journalcode | J01231 | - |
dc.identifier.eissn | 1875-8908 | - |
dc.identifier.pmid | 31640093 | - |
dc.identifier.url | https://content.iospress.com/articles/journal-of-alzheimers-disease/jad190521 | - |
dc.contributor.alternativeName | Park, Byoung Jin | - |
dc.contributor.affiliatedAuthor | 박병진 | - |
dc.contributor.affiliatedAuthor | 심재용 | - |
dc.citation.volume | 72 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 803 | - |
dc.citation.endPage | 814 | - |
dc.identifier.bibliographicCitation | Journal of Alzheimers Disease, Vol.72(3) : 803-814, 2019 | - |
dc.identifier.rimsid | 64338 | - |
dc.type.rims | ART | - |
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