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Transoral robotic surgery in patients with stage III/IV hypopharyngeal squamous cell carcinoma: treatment outcome and prognostic factor

Authors
 Young Min Park  ;  Da Hee Kim  ;  Min Seok Kang  ;  Jae Yol Lim  ;  Yoon Woo Koh  ;  Se-Heon Kim 
Citation
 ACTA OTO-LARYNGOLOGICA, Vol.139(9) : 816-822, 2019 
Journal Title
ACTA OTO-LARYNGOLOGICA
ISSN
 0001-6489 
Issue Date
2019
Keywords
Transoral robotic surgery ; advanced stage ; hypopharyngeal cancer ; margin status ; organ-preserving surgical treatment
Abstract
Background: We aimed to reduce the morbidity related to treatment and to preserve organ function in patients with hypopharyngeal squamous cell carcinoma (HPSCC) by applying a new surgical treatment protocol based on transoral robotic surgery (TORS). Aims/objectives: In this study, we analyzed the prognostic factors related to survival to confirm the validity and effectiveness of TORS in patients with advanced-stage HPSCC. Methods: We retrospectively analyzed the data of 44 HPSCC patients who had undergone TORS-based therapy. Results: In univariate analysis, only the surgical marginal status showed a statistically significant correlation with the survival of the patients (p = .009). In multivariate analysis, surgical margin status was the only statistically significant prognostic factor related to survival (p = .008). Forty-one patients (93.2%) recovered speech function sufficiently to perform daily conversation without artificial aids. Forty-one patients (93.2%) were able to ingest food orally. Conclusions: In the treatment of advanced hypopharyngeal cancer, TORS-based therapy helped the surgeon obtain a clear surgical margin in patients with HPSCC, and it showed superior oncologic and functional outcomes compared to the existing treatment methods.
Full Text
https://www.tandfonline.com/doi/full/10.1080/00016489.2019.1631480
DOI
10.1080/00016489.2019.1631480
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Otorhinolaryngology (이비인후과학교실) > 1. Journal Papers
Yonsei Authors
Koh, Yoon Woo(고윤우)
Kim, Da Hee(김다희) ORCID logo https://orcid.org/0000-0001-7286-1334
Kim, Se Heon(김세헌)
Park, Young Min(박영민) ORCID logo https://orcid.org/0000-0002-7593-8461
Lim, Jae Yol(임재열) ORCID logo https://orcid.org/0000-0002-9757-6414
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/174794
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