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Long-term Outcomes of Antiviral Therapy in Patients With Advanced Chronic HBV Infection

Authors
 Hye Won Lee  ;  Jun Yong Park  ;  Sang Gyune Kim  ;  Won Young Tak  ;  Hyung Joon Yim  ;  Byoung Kuk Jang  ;  Moon Young Kim  ;  Byung Ik Kim  ;  Jin-Woo Lee  ;  Ki Tae Yoon  ;  Jae Youn Cheong  ;  So Young Kwon  ;  Tae Yeob Kim  ;  Si Hyun Bae  ;  Yeon Seok Seo  ;  Jung Hyun Kwon  ;  Dong Joon Kim  ;  Ja-Kyung Kim  ;  Soung Won Jeong  ;  Sungmin Myoung  ;  Sang Hoon Ahn  ;  Kwang-Hyub Han 
Citation
 CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, Vol.17(13) : 2811-2813.e1, 2019 
Journal Title
 CLINICAL GASTROENTEROLOGY AND HEPATOLOGY 
ISSN
 1542-3565 
Issue Date
2019
Abstract
Hepatitis B virus (HBV) suppression with nucleot(s)ide analogue therapy reduces the risk of hepatic decompensation and hepatocellular carcinoma (HCC) in patients with advanced liver disease.1 In the present era of potent antiviral therapies, the prognostic significance of the serum HBV DNA level as a biological gradient has substantially diminished; the majority of treated patients achieve virologic suppression.2,3 After control of viremia, a higher baseline fibrosis level is a useful predictor for disease progression.4 Few "prospective" studies on the effects of antiviral agents, especially in chronic hepatitis B (CHB) patients with advanced liver disease, have been reported.
Full Text
https://www.sciencedirect.com/science/article/pii/S1542356519300916
DOI
10.1016/j.cgh.2019.01.044
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Ja Kyung(김자경) ORCID logo https://orcid.org/0000-0001-5025-6846
Park, Jun Yong(박준용) ORCID logo https://orcid.org/0000-0001-6324-2224
Ahn, Sang Hoon(안상훈) ORCID logo https://orcid.org/0000-0002-3629-4624
Lee, Hye Won(이혜원) ORCID logo https://orcid.org/0000-0002-3552-3560
Han, Kwang-Hyub(한광협) ORCID logo https://orcid.org/0000-0003-3960-6539
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/174711
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