Cited 4 times in
Bioactive characteristics of an implant surface coated with a pH buffering agent: an in vitro study
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 배형철 | - |
dc.contributor.author | 백정원 | - |
dc.contributor.author | 송영우 | - |
dc.contributor.author | 차재국 | - |
dc.contributor.author | 최성호 | - |
dc.date.accessioned | 2020-02-11T06:28:09Z | - |
dc.date.available | 2020-02-11T06:28:09Z | - |
dc.date.issued | 2019 | - |
dc.identifier.issn | 2093-2278 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/174690 | - |
dc.description.abstract | Purpose: The purpose of this study was to evaluate the effectiveness of conventional sandblasted, large-grit, acid-etched (SLA) surface coated with a pH buffering solution based on surface wettability, blood protein adhesion, osteoblast affinity, and platelet adhesion and activation. Methods: Titanium discs and implants with conventional SLA surface (SA), SLA surface in an aqueous calcium chloride solution (CA), and SLA surface with a pH buffering agent (SOI) were prepared. The wetting velocity was measured by the number of threads wetted by blood over an interval of time. Serum albumin adsorption was tested using the bicinchoninic acid assay and by measuring fluorescence intensity. Osteoblast activity assays (osteoblast adhesion, proliferation, differentiation, mineralization, and migration) were also performed, and platelet adhesion and activation assays were conducted. Results: In both the wetting velocity test and the serum albumin adsorption assay, the SOI surface displayed a significantly higher wetting velocity than the SA surface (P=0.000 and P=0.000, respectively). In the osteoblast adhesion, proliferation, differentiation, and mineralization tests, the mean values for SOI were all higher than those for SA and CA. On the osteoblast migration, platelet adhesion, and activation tests, SOI also showed significantly higher values than SA (P=0.040, P=0.000, and P=0.000, respectively). Conclusions: SOI exhibited higher hydrophilicity and affinity for proteins, cells, and platelets than SA. Within the limits of this study, it may be concluded that coating an implant with a pH buffering agent can induce the attachment of platelets, proteins, and cells to the implant surface. Further studies should be conducted to directly compare SOI with other conventional surfaces with regard to its safety and effectiveness in clinical settings. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Korean Academy of Periodontology | - |
dc.relation.isPartOf | JOURNAL OF PERIODONTAL AND IMPLANT SCIENCE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Bioactive characteristics of an implant surface coated with a pH buffering agent: an in vitro study | - |
dc.type | Article | - |
dc.contributor.college | College of Dentistry (치과대학) | - |
dc.contributor.department | Dept. of Periodontics (치주과학교실) | - |
dc.contributor.googleauthor | Hyung-Chul Pae | - |
dc.contributor.googleauthor | Su-Kyoung Kim | - |
dc.contributor.googleauthor | Jin-Young Park | - |
dc.contributor.googleauthor | Young Woo Song | - |
dc.contributor.googleauthor | Jae-Kook Cha | - |
dc.contributor.googleauthor | Jeong-Won Paik | - |
dc.contributor.googleauthor | Seong-Ho Choi | - |
dc.identifier.doi | 10.5051/jpis.2019.49.6.366 | - |
dc.contributor.localId | A05596 | - |
dc.contributor.localId | A01836 | - |
dc.contributor.localId | A05142 | - |
dc.contributor.localId | A04004 | - |
dc.contributor.localId | A04081 | - |
dc.relation.journalcode | J01695 | - |
dc.identifier.eissn | 2093-2286 | - |
dc.identifier.pmid | 31886029 | - |
dc.subject.keyword | Biocompatible coated materials | - |
dc.subject.keyword | Dental implants | - |
dc.subject.keyword | Immunoassay | - |
dc.subject.keyword | Surface properties | - |
dc.contributor.alternativeName | Pae, Hyung-Chul | - |
dc.contributor.affiliatedAuthor | 배형철 | - |
dc.contributor.affiliatedAuthor | 백정원 | - |
dc.contributor.affiliatedAuthor | 송영우 | - |
dc.contributor.affiliatedAuthor | 차재국 | - |
dc.contributor.affiliatedAuthor | 최성호 | - |
dc.citation.volume | 49 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 366 | - |
dc.citation.endPage | 381 | - |
dc.identifier.bibliographicCitation | JOURNAL OF PERIODONTAL AND IMPLANT SCIENCE, Vol.49(6) : 366-381, 2019 | - |
dc.identifier.rimsid | 63472 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.