15 31

Cited 1 times in

Characteristics of Lung Allocation and Outcomes of Lung Transplant according to the Korean Urgency Status

Authors
 Woo Sik Yu  ;  Song Yee Kim  ;  Young Tae Kim  ;  Hyun Joo Lee  ;  Samina Park  ;  Sun Mi Choi  ;  Do Hyung Kim  ;  Woo Hyun Cho  ;  Hye Ju Yeo  ;  Seung-il Park  ;  Se Hoon Choi  ;  Sang-Bum Hong  ;  Tae Sun Shim  ;  Kyung-Wook Jo  ;  Kyeongman Jeon  ;  Byeong-Ho Jeong  ;  Hyo Chae Paik  ;  Jin Gu Lee  ;  Korean Organ Transplantation Registry Study Group 
Citation
 YONSEI MEDICAL JOURNAL, Vol.60(10) : 992-997, 2019 
Journal Title
 YONSEI MEDICAL JOURNAL 
ISSN
 0513-5796 
Issue Date
2019
MeSH
Female ; Humans ; Lung Transplantation* ; Male ; Middle Aged ; Postoperative Care ; Registries ; Republic of Korea ; Survival Analysis ; Treatment Outcome
Keywords
Lung transplant ; lung allocation ; post-transplant survival
Abstract
PURPOSE: We investigated the characteristics of lung allocation and outcomes of lung transplant (LTx) according to the Korean urgency status. MATERIALS AND METHODS: LTx registration in the Korean Organ Transplantation Registry (KOTRY) began in 2015. From 2015 to June 2017, 86 patients who received LTx were enrolled in KOTRY. After excluding one patient who received a heart-lung transplant, 85 were included. Subjects were analyzed according to the Korean urgency status. RESULTS: Except for Status 0, urgency status was classified based on partial pressure of oxygen in arterial blood gas analysis and functional status in 52 patients (93%). The wait time for lung allograft was well-stratified by urgency (Status 0, 46.5±59.2 days; Status 1, 104.4±98.2 days; Status 2 or 3, 132.2±118.4 days, p=0.009). Status 0 was associated with increased operative times and higher intraoperative blood transfusion. Status 0 was associated with prolonged extracorporeal membrane oxygenation use, postoperative bleeding, and longer mechanical ventilation after operation. Survival of Status 0 patients seemed worse than that of non-Status 0 patients, although differences were not significant. CONCLUSION: The Korean urgency classification for LTx is determined by using very limited parameters and may not be a true reflection of urgency. Status 0 patients seem to have poor outcomes compared to the other urgency status patients, despite having the highest priority for donor lungs. Further multi-center and nationwide studies are needed to revise the lung allocation system to reflect true urgency and provide the best benefit of lung transplantation.
Files in This Item:
T201903568.pdf Download
DOI
10.3349/ymj.2019.60.10.992
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Thoracic and Cardiovascular Surgery (흉부외과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Song Yee(김송이) ORCID logo https://orcid.org/0000-0001-8627-486X
Paik, Hyo Chae(백효채) ORCID logo https://orcid.org/0000-0001-9309-8235
Lee, Jin Gu(이진구)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/174484
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse