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근치적수술과 술후방사선치료를 받은 이하선 악성종양 환자의 치료실패양상 : 병리학적 유형에 따른 결과를 중심으로

Other Titles
 Patterns of Failure after Combined Surgery and Radiation Therapy for Malignant Tumors of the Parotid Gland - Analysis of Treatment Results According to Pathologic Type - 
Authors
 이상욱  ;  장세경  ;  김귀언  ;  서창옥  ;  성진실  ;  이창걸  ;  금기창  ;  박정수  ;  최은창 
Citation
 Korean Journal of Head & Neck Oncology (대한두경부종양학회지), Vol.15(2) : 182-188, 1999 
Journal Title
 Korean Journal of Head & Neck Oncology (대한두경부종양학회지) 
ISSN
 1229-5183 
Issue Date
1999
Keywords
근치적수술 ; 술후방사선치료 ; 이하선악성종양 ; 치료실패양상 ; Parotid gland malignancy ; Surgery ; Radiotherapy
Abstract
Purpose: To investigate the treatment results' and patterns of failure according to the pathologic type of the parotid malignancy who were treated with radical sugery and postoperative radiation therapy. Materials and Methods: Fifty-two patients with various type of the parotid malignancy, who were treated with combined radical surgery and post-operative irradiation at Yonsei Cancer Center, between 1981 and 1995, were retrospectively reviewed after completion treatment, all but one patients were follow up with the median follow up period of 49 months. Results: We found that pathologically confirmed neck node metastasis rate was 28.8% all case and level II was most common site. Overall failure rate was 26.9%, local recurrence rate was 13.5%, node failure rate was 7.7%, and distant failure rate was 5.8%. Five-year disease free survival rate was 70.9%, and overall survival rate was 73.8%. Recurrence rate was low in adenoid cystic carcinoma and acinic cell carcinoma. However distant metastasis was very high in undifferentiated carcinoma. Local recurrence was main pattern of failure in mucoepidermoid carcinoma and nodal failure was frequently observed in adenocarcinoma. Conclusion: Individualized treatment plan may be required to improve a treatment outcome by pathologic subtype of the parotid malignancy.
Files in This Item:
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiation Oncology (방사선종양학교실) > 1. Journal Papers
Yonsei Authors
Seong, Jin Sil(성진실) ORCID logo https://orcid.org/0000-0003-1794-5951
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/174248
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