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Large Cell Calcifying Sertoli Cell Tumor of the Testis : Case Report with Ultrastructural Study

 Jeong Hae Kie  ;  Young Nyun Park  ;  Sang Won Han  ;  Nam Hoon Cho  ;  Jae Yoon Ro 
 International Journal of Surgical Pathology, Vol.7(2) : 109-114, 1999 
Journal Title
 International Journal of Surgical Pathology 
Issue Date
large cell calcifying sertoli cell tumor ; electron microscopy ; Carney syndrome calcifications ; Leydig cell tumor.
Large cell calcifying Sertoli cell tumor (LCCST) is a rare testicular tumor, usually occurring in young men before the age of 20. Ultrastructural study has been performed rarely demonstrating Sertoli cell features. We report a case of LCCST in a 7-year-old boy. A well-circumscribed yellowish-tan, 1.5-cm-sized mass was located within the left testicular parenchyma. The cut surface was somewhat resilient with multiple calcifications. On microscopic examination, the tumor was composed of large eosinophilic polygonal cells with abundant eosinophilic cytoplasm arranging in solid tubular and trabecular patterns, superficially mimicking Leydig cell tumor. However, there were multiple calcifications and the tumor cell nests were surrounded by PASpositive basement membrane. Ultrastructural examination revealed the features of the Sertoli cell with Spangaro's crystals. The right testis showed a normal appearance by ultrasonogram and there were no other clinical features associated with Carney syndrome.
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1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Urology (비뇨의학교실) > 1. Journal Papers
Yonsei Authors
Park, Young Nyun(박영년) ORCID logo https://orcid.org/0000-0003-0357-7967
Cho, Nam Hoon(조남훈) ORCID logo https://orcid.org/0000-0002-0045-6441
Han, Sang Won(한상원) ORCID logo https://orcid.org/0000-0003-0941-1300
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