Cited 44 times in
Effects of 0.005% latanoprost on optic nerve head and peripapillary retinal blood flow
DC Field | Value | Language |
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dc.contributor.author | 성공제 | - |
dc.contributor.author | 이형근 | - |
dc.date.accessioned | 2020-01-10T02:04:53Z | - |
dc.date.available | 2020-01-10T02:04:53Z | - |
dc.date.issued | 1999 | - |
dc.identifier.issn | 0030-3755 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/173855 | - |
dc.description.abstract | Fifty-two eyes of 26 healthy volunteers were recruited for evaluating the effects of 0.005% latanoprost on optic nerve head (ONH) and peripapillary retinal blood flow. In a randomized double-blind design, one eye received one drop of 0.005% latanoprost and its fellow eye received one drop of a placebo eyedrop. Intraocular pressure (IOP), ONH and peripapillary retinal blood flow were measured with Heidelberg retinal flowmetry (HRF) before, 2 and 24 h after administration of eyedrops. IOP was decreased significantly in latanoprost-treated eyes at 2 and 24 h after administration (p < 0.05). In the volume, flow or velocity of ONH and peripapillary retina, there were no significant changes from the baseline values at 2 and 24 h after latanoprost administration in either latanoprost-treated eyes or their fellow eyes (p > 0.05). No significant differences were found in the measured quantities between latanoprost-treated eyes and their fellow eyes at each time point (p > 0.05). This result may suggest that 0.005% latanoprost in healthy subjects does not have any adverse effect on ONH and peripapillary retinal blood flow. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | German | - |
dc.publisher | Karger | - |
dc.relation.isPartOf | Ophthalmologica | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Blood Flow Velocity/drug effects | - |
dc.subject.MESH | Double-Blind Method | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Intraocular Pressure/drug effects | - |
dc.subject.MESH | Laser-Doppler Flowmetry | - |
dc.subject.MESH | Latanoprost | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Ophthalmic Solutions/pharmacology | - |
dc.subject.MESH | Optic Disk/blood supply* | - |
dc.subject.MESH | Optic Disk/drug effects* | - |
dc.subject.MESH | Prostaglandins F, Synthetic/pharmacology* | - |
dc.subject.MESH | Reference Values | - |
dc.subject.MESH | Regional Blood Flow/drug effects | - |
dc.subject.MESH | Reproducibility of Results | - |
dc.subject.MESH | Retinal Vessels/drug effects* | - |
dc.subject.MESH | Retinal Vessels/physiology | - |
dc.title | Effects of 0.005% latanoprost on optic nerve head and peripapillary retinal blood flow | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Ophthalmology (안과학교실) | - |
dc.contributor.googleauthor | Gong Je Seong | - |
dc.contributor.googleauthor | Hyung Keun Lee | - |
dc.contributor.googleauthor | Young Jae Hong | - |
dc.identifier.doi | 10.1159/000027454 | - |
dc.contributor.localId | A01946 | - |
dc.contributor.localId | A03303 | - |
dc.relation.journalcode | J02431 | - |
dc.identifier.eissn | 1423-0267 | - |
dc.identifier.pmid | 10567866 | - |
dc.identifier.url | https://www.karger.com/Article/FullText/27454 | - |
dc.contributor.alternativeName | Seong, Gong Je | - |
dc.contributor.affiliatedAuthor | 성공제 | - |
dc.contributor.affiliatedAuthor | 이형근 | - |
dc.citation.volume | 213 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 355 | - |
dc.citation.endPage | 359 | - |
dc.identifier.bibliographicCitation | Ophthalmologica, Vol.213(6) : 355-359, 1999 | - |
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