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Antibodies to human T-cell lymphotropic virus type I (HTLV-I) by particle agglutination (PA) test in Korean blood donors

Authors
 June Myung Kim  ;  Young Goo Song  ;  Young Chul Oho  ;  Hyeong Cheon Park  ;  Kun Ho Kwon  ;  Eung Kim  ;  Seon Ho Lee  ;  Ki Hong Kim 
Citation
 YONSEI MEDICAL JOURNAL, Vol.40(2) : 173-177, 1999 
Journal Title
 YONSEI MEDICAL JOURNAL 
ISSN
 0513-5796 
Issue Date
1999
MeSH
Adolescent ; Adult ; Age Distribution ; Agglutination Tests* ; Blood Donors* ; Child ; Female ; HTLV-I Antibodies/blood* ; Humans ; Korea ; Male ; Sex Distribution
Abstract
HTLV-I infection is a recently recognized disease entity that is common in some tropical and subtropical areas, including the southwestern district of Japan. Despite the geographical proximity and frequent cultural exchanges between Korea and Japan, it is understood that Korea is not an endemic area and HTLV-I-associated illnesses are very rare in Korea. This study was designed to evaluate the positive rate of anti-HTLV-I antibodies in Korean blood donors and its regional distribution. Sera were obtained from blood donors from various districts around Korea. Anti-HTLV-I antibodies were detected by using the microtiter particle agglutination test employing an indirect agglutination technique. A total of 9,281 donors were tested and 12 donors (0.13%) were positive for anti-HTLV-I antibodies, 10 (0.11%) out of 8,845 males and 2 (0.46%) out of 436 females, with relative female predominance. A relatively high incidence of anti-HTLV-I positive donors was observed in Cheju Island (0.80%), Kyungnam (0.31%), and Chonnam (0.15%). In conclusion, the positive rate of anti-HTLV-I antibodies seemed to be very low in Korea, but the highest positive rate of anti-HTLV-I antibodies was noticed on Cheju Island, warranting further research for confirmation.
Files in This Item:
T199901149.pdf Download
DOI
10.3349/ymj.1999.40.2.173
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kim, June Myung(김준명)
Park, Hyeong Cheon(박형천) ORCID logo https://orcid.org/0000-0002-1550-0812
Song, Young Duk(송영득)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/173805
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