162 287

Cited 1 times in

Impact of metabolic syndrome-related factors on the development of benign prostatic hyperplasia and lower urinary tract symptoms in Asian population

DC Field Value Language
dc.contributor.author구교철-
dc.contributor.author박지수-
dc.contributor.author이광석-
dc.contributor.author정병하-
dc.contributor.author김혜경-
dc.date.accessioned2019-12-18T00:39:58Z-
dc.date.available2019-12-18T00:39:58Z-
dc.date.issued2019-
dc.identifier.issn0025-7974-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/173163-
dc.description.abstractThis study aimed to investigate the metabolic syndrome-related risk factors for the development of benign prostatic hyperplasia (BPH) with lower urinary tract symptoms (LUTS) in healthy men.A total of 4880 healthy men who underwent transrectal ultrasonography at our hospital during routine health examinations were included in this study. Those who had undergone a prior biopsy or surgery for prostate disease, were suspected of having urinary tract infection, or were taking BPH/LUTS or metabolic syndrome medications were excluded. BPH/LUTS was defined as an International Prostate Symptom Score (IPSS) of ≥8 and a prostate volume (PV) of ≥30 cm.The subjects had a mean age of 54.1 years, PV of 29.2 cm, prostate-specific antigen (PSA) level of 1.20 ng/mL, and IPSS of 9.2. The annual PV growth rate was 0.48 cm/year. Age, body mass index (BMI), PSA, basal metabolic rate, apolipoprotein A-1, fasting blood glucose, high-density lipoprotein (HDL) cholesterol levels were significant predictive factors for PV. Age, PSA, apolipoprotein B, fasting blood glucose, cholesterol, HDL, and low-density lipoprotein (LDL) levels were predictors of BPH/LUTS at the initial health examination. A decreased fat mass and LDL level were a significant risk factor for the development of BPH/LUTS within 5 years in men without a BPH/LUTS diagnosis at the initial examination.Metabolic syndrome-related variables were strongly associated with BPH/LUTS and by decreasing fat mass and LDL levels, development of BPH/LUTS could be prevented within 5 years in healthy Korean men.-
dc.description.statementOfResponsibilityopen-
dc.formatapplication/pdf-
dc.languageEnglish-
dc.publisherLippincott Williams & Wilkins-
dc.relation.isPartOfMEDICINE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.subject.MESHAged-
dc.subject.MESHBiomarkers/blood-
dc.subject.MESHBiopsy-
dc.subject.MESHBlood Glucose/metabolism-
dc.subject.MESHBody Mass Index-
dc.subject.MESHCholesterol, LDL/blood*-
dc.subject.MESHDisease Progression-
dc.subject.MESHEndosonography-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHHumans-
dc.subject.MESHIncidence-
dc.subject.MESHLower Urinary Tract Symptoms/diagnosis-
dc.subject.MESHLower Urinary Tract Symptoms/epidemiology-
dc.subject.MESHLower Urinary Tract Symptoms/etiology*-
dc.subject.MESHMale-
dc.subject.MESHMetabolic Syndrome/blood-
dc.subject.MESHMetabolic Syndrome/complications*-
dc.subject.MESHMetabolic Syndrome/epidemiology-
dc.subject.MESHMiddle Aged-
dc.subject.MESHPrognosis-
dc.subject.MESHProstate/diagnostic imaging-
dc.subject.MESHProstatic Hyperplasia/diagnosis-
dc.subject.MESHProstatic Hyperplasia/epidemiology-
dc.subject.MESHProstatic Hyperplasia/etiology*-
dc.subject.MESHRectum-
dc.subject.MESHRepublic of Korea/epidemiology-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHRisk Assessment/methods*-
dc.subject.MESHRisk Factors-
dc.titleImpact of metabolic syndrome-related factors on the development of benign prostatic hyperplasia and lower urinary tract symptoms in Asian population-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Urology (비뇨의학교실)-
dc.contributor.googleauthorJee Soo Park-
dc.contributor.googleauthorKyo Chul Koo-
dc.contributor.googleauthorHye Kyung Kim-
dc.contributor.googleauthorByung Ha Chung-
dc.contributor.googleauthorKwang Suk Lee-
dc.identifier.doi10.1097/MD.0000000000017635-
dc.contributor.localIdA00188-
dc.contributor.localIdA05336-
dc.contributor.localIdA05336-
dc.contributor.localIdA02668-
dc.contributor.localIdA02668-
dc.contributor.localIdA03607-
dc.contributor.localIdA03607-
dc.relation.journalcodeJ02214-
dc.identifier.eissn1536-5964-
dc.identifier.pmid31626149-
dc.contributor.alternativeNameKoo, Kyo Chul-
dc.contributor.affiliatedAuthor구교철-
dc.contributor.affiliatedAuthor박지수-
dc.contributor.affiliatedAuthor박지수-
dc.contributor.affiliatedAuthor이광석-
dc.contributor.affiliatedAuthor이광석-
dc.contributor.affiliatedAuthor정병하-
dc.contributor.affiliatedAuthor정병하-
dc.citation.volume98-
dc.citation.number42-
dc.citation.startPagee17635-
dc.identifier.bibliographicCitationMEDICINE, Vol.98(42) : e17635, 2019-
dc.identifier.rimsid63735-
dc.type.rimsART-
Appears in Collections:
6. Others (기타) > Gangnam Severance Hospital Health Promotion Center(강남세브란스병원 체크업) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Urology (비뇨의학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.