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Neural stem cells -- a versatile tool for cell replacement and gene therapy in the central nervous system.

Authors
 V Ourednika  ;  J Ourednika  ;  KI Parkcand  ;  EY Snyder 
Citation
 CLINICAL GENETICS, Vol.56(4) : 267-278, 1999 
Journal Title
 CLINICAL GENETICS 
ISSN
 0009-9163 
Issue Date
1999
MeSH
Animals ; Central Nervous System/injuries ; Central Nervous System/pathology ; Central Nervous System Diseases/pathology ; Central Nervous System Diseases/therapy* ; Clone Cells ; Genetic Engineering ; Genetic Therapy/methods* ; Humans ; Stem Cell Transplantation*
Abstract
In recent years, it has become evident that the developing and even the adult mammalian central nervous system contains a population of undifferentiated, multipotent cell precursors, neural stem cells, the plastic properties of which might be of advantage for the design of more effective therapies for many neurological diseases. This article reviews the recent progress in establishing rodent and human clonal neural stem cell lines, their biological properties, and how these cells can be utilized to a correct variety of defects, with prospects for the near future to harness their behaviour for neural stem cell-based treatment of diseases in humans.
Full Text
https://onlinelibrary.wiley.com/doi/full/10.1034/j.1399-0004.1999.560403.x
DOI
10.1034/j.1399-0004.1999.560403.x
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아청소년과학교실) > 1. Journal Papers
Yonsei Authors
Park, Kook In(박국인) ORCID logo https://orcid.org/0000-0001-8499-9293
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/172840
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