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Chronological changes in incidences of polymorphic reticulosis in Korea and Japan

 Masahiko Ohsawa  ;  Norihisa Shingu  ;  Hidenori Inohara  ;  Takashi Kubo  ;  Woo-Ich Yang  ;  Joo-Hyeon Yoon  ;  Katsuyuki Aozasa 
 ONCOLOGY, Vol.56(3) : 202-207, 1999 
Journal Title
Issue Date
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Child ; DNA, Viral/isolation & purification ; Female ; Granuloma, Lethal Midline/epidemiology* ; Granuloma, Lethal Midline/etiology* ; Granuloma, Lethal Midline/pathology ; Herpesvirus 4, Human/genetics ; Herpesvirus 4, Human/isolation & purification* ; Humans ; Incidence ; Japan/epidemiology ; Korea/epidemiology ; Male ; Middle Aged
Granuloma, lethal midline ; Polymorphic reticulosis ; Japan ; Korea
Lethal midline granuloma (LMG) is a clinical term, which describes a group of diseases histologically comprising Wegener's granulomatosis, polymorphic reticulosis (PR), and malignant lymphoma of the ordinary type (ML). PR is a variant of ML, and is considered to be a type of NK/T cell lymphoma. Our previous study revealed the clustering of patients with PR in East Asia including China, Korea and Japan. However, the frequency rate of PR varied even among these countries, with that of Korea being approximately 5 times higher than that of Japan. In the present study, we examined the incidences of each type of LMG, especially PR, in Korea (Yonsei University) and Japan (59 university hospitals) over time. A total of 102 cases and 655 cases of LMG admitted to Yonsei University, Korea from 1977 to 1996 and 59 university hospitals in Japan between 1965 and 1996, respectively, were examined. The frequency rate of PR per 100,000 outpatients of ears, nose and throat (ENT) clinics in Korea decreased from 40 to 20 between the periods of 1977-1989 and 1990-1996. However, there were no significant changes in Japan during the period studied.
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1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Otorhinolaryngology (이비인후과학교실) > 1. Journal Papers
Yonsei Authors
Yang, Woo Ick(양우익) ORCID logo https://orcid.org/0000-0002-6084-5019
Yoon, Joo Heon(윤주헌)
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